Evaluation of centrifugal blood pumps in term of hemodynamic performance using simulated neonatal and pediatric ECMO circuits

Artificial Organs
Shigang WangAkif Undar

Abstract

The objective of this translational study was to evaluate the FDA-approved PediMag, CentriMag, and RotaFlow centrifugal blood pumps in terms of hemodynamic performance using simulated neonatal and pediatric extracorporeal membrane oxygenation (ECMO) circuits with different sizes of arterial and venous cannulae. Cost of disposable pump heads was another important variable for this particular study. The experimental circuit was composed of one of the centrifugal pump heads, a polymethylpentene membrane oxygenator, neonatal and pediatric arterial/venous cannulae, and 1/4-inch ID tubing. Circuits were primed with lactated Ringer's solution and packed human red blood cells (hematocrit 35%). Trials were conducted at 36°C using the three pump heads and different cannulae (arterial/venous cannulae: 8 Fr/18 Fr, 10 Fr/20 Fr, and 12 Fr/22 Fr) at various flow rates (200-2400 mL/min, 200 mL/min increments) and rotational speeds. Pseudo patient pressure was 60 mm Hg. Real-time pressure and flow data were recorded for analysis. The RotaFlow pump had a higher pressure head and flow range compared with the PediMag and CentriMag pumps at the same rotational speed and identical experimental settings (P < 0.001). The PediMag pump had lower flow ou...Continue Reading

References

Nov 1, 1966·Archives of Surgery·R B ShepardJ F Sharp
Mar 26, 2009·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Shigang WangAkif Undar
Apr 10, 2009·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Shigang WangAkif Undar
Jun 28, 2011·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Antonio LoforteFrancesco Musumeci
Aug 14, 2012·Artificial Organs·Michael A SobieskiMark S Slaughter
Jan 8, 2014·Artificial Organs·David A PalanzoWalter E Pae
Jul 11, 2014·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Oleg BorisenkoRichard Firmin
Oct 28, 2017·Journal of the American College of Cardiology·Vamsi V YarlagaddaChristopher S Almond

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Citations

Sep 19, 2020·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Christian R SargentSabrina Ali

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