Evaluation of chemically-induced phototoxicity to aquatic organism using Paramecium as a model

Biochemical and Biophysical Research Communications
P C Joshi, R B Misra

Abstract

Phototoxicity evaluation using Paramecium aurelia as a model revealed that 4 out of 21 pesticides produced lethal toxicity to cells. Four commonly used synthetic dyes (bromophenol blue, rose bengal, benzanthrone and methylene blue) also exhibited toxicity. Well known phototoxic agents like hematoporphyrin, riboflavin, and anthracene produced positive phototoxic response. Psoralen, a DNA cross-linking agent, also produced phototoxicity to the cells. The results clearly demonstrate that the synergistic action of chemical agents and sunlight produce lethal effects to aquatic organism.

Citations

Jul 1, 1992·Toxicology in Vitro : an International Journal Published in Association with BIBRA·S Kumar, P C Joshi
Sep 1, 1990·Journal of Photochemistry and Photobiology. B, Biology·R LalwaniS Mukherji
Oct 12, 2005·Ecotoxicology and Environmental Safety·R B MisraR K Hans
Mar 22, 2001·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·R B MisraR K Hans
Nov 1, 1990·Photochemistry and Photobiology·R W TuvesonJ Kagan
Sep 1, 1992·Photochemistry and Photobiology·M R RichS S Brody
May 1, 1997·Photochemistry and Photobiology·F Saitow, Y Nakaoka
Jun 4, 2015·PloS One·Javier Ignacio BianchiSergio Hernán Simonetta
Dec 1, 1993·Journal of Photochemistry and Photobiology. B, Biology·E M Tuite, J M Kelly

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