PMID: 6403730Jan 1, 1983Paper

Evaluation of clinical and biological parameters in marastic Kwashiorkor children treated by parenteral nutrition

JPEN. Journal of Parenteral and Enteral Nutrition
F JanssenH L Vis

Abstract

Reduction of hospital stay and mortality rate due to dehydration and electrolyte imbalance in children suffering from severe marasmic Kwashiorkor was attempted. A program of parenteral nutrition providing 70 to 100 milliliters water, 30 to 40 kilocalories, and 3 to 4 grams amino acids per kilogram daily was given. Seventy-seven African children suffering from protein deficiency and calorie deficiency were given an intravenous perfusion of casein hydrolysate or cristalloid amino acids for a mean period of 6 days. An oral supplement of tea and sugar, boiled rice, and palm oil was also given. The total mortality has not been modified in comparison with that in children given an oral diet (semi-liquid) consisting of low fat milk and locally available proteins. In more than half of the cases, the parenteral nutrition has favored water and salt retention and the development of cardiac failure possibly due to adynamic circulatory state. Weight curve, serum albumins, serum and urine amino acids were followed closely for 1 month. In eleven patients, nitrogen balance studies were done. All were positive independently of the coexisting infectious pathology. Correlating the increase in serum proteins with the cumulative nitrogen balance al...Continue Reading

References

Mar 1, 1977·The American Journal of Clinical Nutrition·P Viart
Jun 1, 1977·European Journal of Clinical Investigation·P Fondu
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Feb 1, 1969·Postgraduate Medical Journal·H L Vis
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Feb 1, 1962·The Journal of Pediatrics·H E SCHENDEL, J D HANSEN
Sep 1, 1956·The Journal of Tropical Pediatrics·Federico GomezJudith Vazquez

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Citations

Nov 1, 1994·Indian Journal of Pediatrics·A G Thomas
Oct 1, 2013·Pharmacological Reviews·Gavril W Pasternak, Ying-Xian Pan

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