PMID: 9636787Jan 1, 1996Paper

Evaluation of cognitive functions after anesthesia with propofol

Annales Françaises D'anesthèsie Et De Rèanimation
J SanouP Erny

Abstract

To assess the disturbances and delay of recovery of cognitive functions following propofol anaesthesia, and to evaluate a series of simple cognitive recovery tests. Prospective comparative non randomized clinical study. Two groups of non premedicated patients, of ASA physical class 1 and 2 were studied. The control group (n = 11) included patients undergoing gastric fibroscopy under local anaesthesia. The propofol group (n = 22) consisted of patients scheduled for coloscopy under propofol anaesthesia. The gastric fibroscopy was performed under local anaesthesia with lidocaine and the coloscopy under general anaesthesia with propofol as the sole anaesthetic. Five cognitive tests, designed to assess short-term memory, delayed memory, the ability to plan complex tasks, attention, and language comprehension were conducted the day before, and 1 hour, 3 hours and 6 hours after the endoscopy. The cognitive functions remained significantly depressed for at least 3 hours after anaesthesia, and recovered fully about 6 hours after the cessation of propofol administration. The capacity for planning was the most heavily affected. Complete recovery can be evaluated by simple cognitive tests, which showed that cognitive functions are impaired...Continue Reading

Citations

Jul 6, 2006·International Journal of Legal Medicine·S SeidlP Betz
Apr 9, 2005·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Franck HamardMarc Laffon

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