Evaluation of commercial implants with nanoindentation defines future development needs for hydroxyapatite coatings

Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Kārlis A GrossKarina S Heemann

Abstract

The performance of biomedical implants relies on the ability to assess and refine the microstructure of biomaterials. Instrumented nanoindentation was applied to determine the mechanical properties of plasma sprayed hydroxyapatite-coated implants from different commercial vendors. All biomedical devices contained both amorphous and crystalline phases. Nanoindentation of the amorphous phase revealed a hardness of 1.5 + or - 0.3 GPa and an elastic modulus of 48 + or - 6 GPa. The crystalline phase revealed a range in hardness of 3.0-7.7 GPa. The large range is attributed to the presence of porosity, surrounding amorphous areas, and hydroxyapatite (unmolten particle cores and recrystallized hydroxyapatite). A selection of the powder type (spray-dried or sintered) leads to different mechanical properties within the coating. A spray-dried powder provides a lower hardness and elastic modulus when unmolten particle cores are included in the coating. Meanwhile recrystallized areas are intermediate in hardness. The combination of a polished cross-section and nanoindentation offers the ability to determine a range of quality control tests including hardness, elastic modulus, bond strength, fracture toughness, substrate and coating roughne...Continue Reading

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Citations

Aug 27, 2013·Acta Biomaterialia·Saeed Saber-SamandariKarlis A Gross
Jun 15, 2010·Biomaterials·Saeed Saber-Samandari, Kārlis A Gross
Apr 5, 2011·Journal of Materials Science. Materials in Medicine·L AltomareN Stiegler
Jun 29, 2015·Materials Science & Engineering. C, Materials for Biological Applications·Sergey V Dorozhkin
Nov 10, 2012·Journal of the Mechanical Behavior of Biomedical Materials·Saeed Saber-Samandari, Karlis A Gross
Jul 26, 2011·Acta Biomaterialia·Saeed Saber-Samandari, Karlis A Gross
Oct 5, 2010·Acta Biomaterialia·Saeed Saber-SamandariKarlis A Gross
Nov 21, 2012·Acta Biomaterialia·Saeed Saber-Samandari, Karlis A Gross
Nov 22, 2011·Journal of the Mechanical Behavior of Biomedical Materials·R AhmedK A Khor
Jan 13, 2015·Materials Science & Engineering. C, Materials for Biological Applications·Amir A Zadpoor
Mar 25, 2010·Journal of Materials Science. Materials in Medicine·P J WalshF J Buchanan
Jun 15, 2018·Journal of Biomedical Materials Research. Part a·Farhad GhadamiHossein Gholami
Mar 2, 2021·Materials Science & Engineering. C, Materials for Biological Applications·Duy Quang PhamAndrew Siao Ming Ang
Apr 5, 2021·Materials Science & Engineering. C, Materials for Biological Applications·Mahsa Asadniaye FardjahromiMajid Ebrahimi Warkiani

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