Evaluation of corneal endothelial cell damage after vitreoretinal surgery: comparison of different endotamponades

Eye
E CinarC Kucukerdonmez

Abstract

We evaluated corneal endothelial cell (EC) damage after vitreoretinal surgery and compared the results using different tamponades. This prospective controlled study included 45 eyes of 45 patients (24 females, 21 males) who underwent pars plana vitrectomy with gas (sulphur hexafluoride, SF6, 20%) or silicone oil (SO) tamponade. Patients were assigned to one of the three groups: group 1 (phakic, 20% SF6 gas), group 2 (pseudophakic, 20% SF6 gas), and group 3 (phakic, SO). Mean endothelial cell density (MCD), mean cell area (MCA), coefficient of variation in cell size (CV), and percentage of hexagonal cells (HC) values were measured using a non-contact specular microscope (SP-2000P; Topcon, Japan) at baseline and at 3 months after surgery. The fellow eye of each patient was used as a control. Group 2, which had the lowest baseline MCD and MCA values, was found to be different than groups 1 and 3 (P=0.028 and 0.022, respectively). At 3 months postoperatively, all groups showed significantly lower MCD, HC and CV values than at baseline (all P<0.05). The mean changes in MCD at 3 months after surgery were 3.8±2.8% (mean±SD), 8.0±7.5%, and 4.6±5.4% in groups 1-3, respectively. The mean MCD changes in the fellow eyes were 0.31±1.41% in ...Continue Reading

References

Jun 1, 1989·Klinische Monatsblätter für Augenheilkunde·F Schulze, H Schmidtsdorf
Jan 1, 1986·Ophthalmology·S I RosenfeldM Gordon
Feb 1, 1987·Archives of Ophthalmology·G N FoulksJ Hardin
Sep 1, 1974·Archives of Ophthalmology·H M LeibowitzM Sandstrom
Oct 15, 1984·American Journal of Ophthalmology·R O SchultzK J Schultz
Jun 1, 1981·Archives of Ophthalmology·J G Slingsby, S L Forstot
Sep 1, 1981·American Journal of Ophthalmology·R A Eiferman, E L Wilkins
Nov 1, 1994·Archives of Ophthalmology·S DuttC A Puliafito
Mar 29, 2001·Experimental Eye Research·M K KoJ G Chi
Apr 13, 2004·Cornea·Ma Dominga B PadillaClarissa S A Gonzales
Dec 31, 2010·Japanese Journal of Ophthalmology·Dong Hyun Jee, Hyun Seung Kim
Feb 3, 2012·Japanese Journal of Ophthalmology·Taehoon OhHyunseung Kim

❮ Previous
Next ❯

Citations

Dec 20, 2017·International Ophthalmology·Hande Guclu, Vuslat Gurlu
Apr 18, 2019·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Adam Kopecky, Jan Nemcansky
Jul 18, 2019·Eye & Contact Lens·Tso-Wen WangJiunn-Liang Chen
Dec 26, 2018·Journal of Ophthalmology·Piotr Kanclerz, Andrzej Grzybowski
Mar 21, 2017·Documenta Ophthalmologica. Advances in Ophthalmology·Akira WatanabeHiroshi Tsuneoka
May 15, 2021·Macromolecular Bioscience·Cristina Mondelo-GarcíaFrancisco J Otero-Espinar
Jun 27, 2021·Journal français d'ophtalmologie·S ZinaM Khairallah
Jul 9, 2021·Scientific Reports·Machiko Shimmura-TomitaAkihiro Kakehashi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.