Evaluation of deep convolutional neural networks for glaucoma detection

Japanese Journal of Ophthalmology
Sang PhanJapan Ocular Imaging Registry Research Group

Abstract

To investigate the performance of deep convolutional neural networks (DCNNs) for glaucoma discrimination using color fundus images STUDY DESIGN: A retrospective study PATIENTS AND METHODS: To investigate the discriminative ability of 3 DCNNs, we used a total of 3312 images consisting of 369 images from glaucoma-confirmed eyes, 256 images from glaucoma-suspected eyes diagnosed by a glaucoma expert, and 2687 images judged to be nonglaucomatous eyes by a glaucoma expert. We also investigated the effects of image size on the discriminative ability and heatmap analysis to determine which parts of the image contribute to the discrimination. Additionally, we used 465 poor-quality images to investigate the effect of poor image quality on the discriminative ability. Three DCNNs showed areas under the curve (AUCs) of 0.9 or more. The AUC of the DCNN using glaucoma-confirmed eyes against nonglaucomatous eyes was higher than that using glaucoma-suspected eyes against nonglaucomatous eyes by approximately 0.1. The image size did not affect the discriminative ability. Heatmap analysis showed that the optic disc area was the most important area for the discrimination of glaucoma. The image quality affected the discriminative ability, and the ...Continue Reading

References

Feb 21, 2006·The British Journal of Ophthalmology·H A Quigley, A T Broman
Nov 30, 2016·JAMA : the Journal of the American Medical Association·Varun GulshanDale R Webster
Jan 10, 2018·Investigative Ophthalmology & Visual Science·Sripad Krishna DevallaMichaël J A Girard
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Jun 20, 2018·American Journal of Ophthalmology·Siamak YousefiKenji Yamanishi

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Citations

Aug 3, 2020·Current Opinion in Ophthalmology·Baseer U AhmadEhsan Rahimy
Jun 14, 2020·The British Journal of Ophthalmology·Darren Shu Jeng TingDaniel Shu Wei Ting
Apr 24, 2020·Eye and Vision·Yan TongYin Shen
Jan 29, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Feng LiKaiqian Zhou
Jan 14, 2021·Medical & Biological Engineering & Computing·Law Kumar SinghRobin Singh Bhadoria
Dec 12, 2020·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Bala PrabhakarKhushwant S Yadav
Feb 7, 2020·Medical Image Analysis·Gwenolé QuellecBéatrice Cochener
Jun 30, 2019·Journal of Stomatology, Oral and Maxillofacial Surgery·A Fourcade, R H Khonsari
Jul 23, 2021·Translational Vision Science & Technology·Christopher BowdLinda M Zangwill
Sep 11, 2021·Clinical & Experimental Ophthalmology·Mathieu BuissonFrédéric Dutheil
Oct 15, 2021·Scientific Reports·Ruben HemelingsIngeborg Stalmans

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