Evaluation of defibrillation safety and shock reduction in implantable cardioverter-defibrillator patients with increased time to detection: A randomized SANKS study

Journal of Arrhythmia
Mahito NoroKaoru Sugi

Abstract

The need for ways to minimize the number of implantable cardioverter-defibrillator (ICD) shocks is increasing owing to the risk of its adverse effects on life expectancy. Studies have shown that a longer detection time for ventricular tachyarrhythmia reduces the safety of therapies, in terms of syncope and mortality, but not substantially in terms of the success rate. We aimed to evaluate the effects of increased number of intervals to detect (NID) VF on the safety of ICD shock therapy and on the reduction of inappropriate shocks. The present study was a prospective, multicenter, randomized, crossover study. Randomized VF induction testing with NID 18/24 or 30/40 was performed to compare the success rate of defibrillation with a 25-J shock and the time to detection. Inappropriate shock episodes were simulated retrospectively to evaluate a possibility of episodes avoidable at NID 24/32 and 30/40. Thirty-one consecutive patients implanted with an ICD or cardiac resynchronization therapy-defibrillator (CRT-D) were enrolled in this study. The success rate of defibrillation was 100% in both NID groups at the first shock. The time from VF induction to detection showed a significant increase in the NID 30/40 group (6.16±1.29 s vs. 9.0...Continue Reading

References

Apr 1, 1983·Journal of Electrocardiology·M A Barker-VoelzM P Schollmeyer
Sep 4, 1998·Journal of Cardiovascular Electrophysiology·T TokanoS A Strickberger
Feb 6, 1999·Journal of the American College of Cardiology·S WindeckerA E Epstein
Aug 10, 1999·Journal of the American College of Cardiology·T M HurstB Waldecker
Apr 5, 2008·Journal of the American College of Cardiology·James P DaubertUNKNOWN MADIT II Investigators
Sep 5, 2008·The New England Journal of Medicine·Jeanne E PooleGust H Bardy
Feb 27, 2010·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Michael O SweeneyBruce L Wilkoff
May 25, 2010·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Linda M KallinenCharles C Gornick
Jan 29, 2011·Journal of the American College of Cardiology·Johannes B van ReesMartin J Schalij
Nov 8, 2012·The New England Journal of Medicine·Arthur J MossUNKNOWN MADIT-RIT Trial Investigators

❮ Previous
Next ❯

Citations

Feb 19, 2016·Circulation Journal : Official Journal of the Japanese Circulation Society·Mahito NoroKaoru Sugi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.