Evaluation of Different Sedatives for Colonoscopy

Current Drug Safety
Waseem M SeleemSherief Abd-Elsalam

Abstract

Sedation and analgesia are important elements of endoscopic examinations; sedation for colonoscopy aims to relieve patient discomfort and anxiety, improve the outcome of the examination, diminish the patient's memory of the event and achieve comfortable and technically successful endoscopic procedure. Our prospective study was carried out on 150 patients who were referred for colonoscopy; they were divided into two groups based on the pre-endoscopic sedation given for them: propofol fentanyl or propofol ketamine. Detailed histories, thorough physical examinations, and routine laboratory investigations were performed for all patients, along with monitoring of their vital signs and oxygen saturation levels (before, during and after colonoscopy), to assess safety, efficacy, recovery times, complications of the sedative drugs, comfort of the patients and endoscopists. There was no statistically significant difference between the two groups in terms of age, sex and Body Mass Indexes (BMI). With respect to their Mean Arterial Blood Pressures (MAPs) and heart rates, there was high hemodynamic stability in the propofol ketamine group, and both the groups were efficacious, although the propofol fentanyl group had shorter recovery times ...Continue Reading

References

Apr 20, 2002·Anesthesiology·UNKNOWN American Society of Anesthesiologists Task Force on Sedation and Analgesia by Non-Anesthesiologists
Oct 25, 2002·Gastrointestinal Endoscopy·Douglas O FaigelUNKNOWN Standards Practice Committe, American Society for Gastrointestinal Endoscopy
Jul 21, 2004·Journal of Clinical Anesthesia·Annelies T MoermanEric P Mortier
Aug 6, 2005·AACN Clinical Issues·Janean E HoldenJeannine M Forrest
Apr 26, 2008·BMJ : British Medical Journal·Gordon H GuyattUNKNOWN GRADE Working Group
Oct 9, 2008·Acta Anaesthesiologica Scandinavica·M VettorelloF Raimondi
Dec 8, 2009·Gastrointestinal Endoscopy·John J VargoPaul Y Kwo
Mar 16, 2011·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Gary Andolfatto, Elaine Willman
May 26, 2012·Gastrointestinal Endoscopy·UNKNOWN American Association for Study of Liver DiseasesLawrence R Schiller
Sep 12, 2015·Psychopathology·Albert R PowersPhilip R Corlett
Jan 31, 2016·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·Angela SmithPaul N Austin

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