Abstract
Evidence suggests that the relationship between arsenic metabolism and diseases, including metabolic syndrome, is complex. The aim of this study was to evaluate the different types of arsenic methylation and its association with metabolic syndrome in an arsenic endemic area. A cross-sectional study was conducted on 132 subjects from Shahid-Abad Village, Qazvin province, Iran (arsenic endemic area). Demographic characteristics, metabolic syndrome, and urinary arsenic species, including iAs (inorganic arsenic), MMA (monomethylarsonic acid), and DMA (dimethylarsinic acid) were measured for all patients and their relationship was analyzed by appropriate statistical methods. In this study, 34.5% of the participants had metabolic syndrome. The decrease in %MMA, increase in %DMA and increase in secondary methylation index (DMA/MMA) were associated with increased risk of metabolic syndrome (p<0.05). We did not find any association between the incidence of metabolic syndrome with primary methylation index (MMA/iAs) and %iAs (p>0.05). This study showed that the prevalence of metabolic syndrome was significantly higher in people with metabolic syndrome than in the general population. A closer examination revealed that the secondary methyl...Continue Reading
References
Sep 26, 1997·Stroke; a Journal of Cerebral Circulation·H Y ChiouC J Chen
Sep 27, 2000·Archives of Toxicology·M StybloD J Thomas
Dec 16, 2004·The Journal of Clinical Investigation·Shigetada FurukawaIichiro Shimomura
Jul 26, 2005·Toxicology and Applied Pharmacology·Chin-Hsiao TsengYu-Mei Hsueh
May 12, 2006·Journal of Occupational and Environmental Medicine·Craig SteinmausAllan H Smith
May 8, 2007·Environment International·Shu-Li WangDennis P H Hsieh
Nov 3, 2010·Reviews on Environmental Health·Tetsuro AgusaShinsuke Tanabe
Nov 17, 2010·Reproductive Toxicology·Renee M GardnerMarie Vahter
Dec 6, 2011·Environmental Health Perspectives·Lalita N AbhyankarAna Navas-Acien
Mar 24, 2012·Chemosphere·Jein-Wen ChenWan-Fen Li
Dec 12, 2012·International Journal of Environmental Research and Public Health·Mohammad Rafiqul IslamAbul Hasnat Milton
May 8, 2013·Environmental Science and Pollution Research International·Xin LiGuifan Sun
Jun 14, 2013·Toxicological Sciences : an Official Journal of the Society of Toxicology·Md Rezaul KarimKhaled Hossain
Oct 29, 2013·Journal of the American College of Cardiology·Nihar R DesaiMarc S Sabatine
Nov 7, 2014·Environmental Health : a Global Access Science Source·Adrienne S EttingerAmy Luke
Nov 20, 2014·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·S O'Neill, L O'Driscoll
Dec 11, 2014·International Archives of Occupational and Environmental Health·Beata JanasikWojciech Wasowicz
Apr 8, 2015·International Journal of Hygiene and Environmental Health·Qing PengSung Kyun Park
Jun 13, 2015·Environmental Health Perspectives·Michelle A MendezMiroslav Stýblo
Dec 15, 2015·Trends in Cardiovascular Medicine·Scott M Grundy
Jun 22, 2016·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Clare PaceJeff Angermann
Sep 21, 2016·Biological Trace Element Research·Prashantkumar WagheSantosh Kumar Mishra
Sep 21, 2016·Pakistan Journal of Medical Sciences·Asher FawwadAbdul Basit
Dec 23, 2016·Journal of Environmental Sciences (China)·Simon Foster, William Maher
Jan 25, 2018·International Journal of Environmental Research and Public Health·Clare PaceJeff Angermann
Mar 20, 2018·American Journal of Epidemiology·Miranda J SpratlenAna Navas-Acien
Aug 16, 2018·Cyberpsychology, Behavior and Social Networking·Sun Jae MoonJung Won Kim
Sep 29, 2019·Pulmonology·Afroditi K Boutou, Theodoros Kontakiotis