Evaluation of disease activity in ankylosing spondylitis; diagnostic value of color Doppler ultrasonography.

Skeletal Radiology
Afshin MohammadiParia Baradaransafa

Abstract

Spondyloarthropathies including ankylosing spondylitis (AS) require early diagnosis to prevent irreversible changes. Sacroiliitis is a common initial manifestation of AS and is frequently diagnosed by magnetic resonance imaging (MRI). The goal of our study was to assess color Doppler ultrasonography as a potential diagnostic tool in suspected sacroiliitis in comparison with MRI representing the gold standard. Fifty-one consecutive patients with AS and sacroiliitis and 30 control subjects underwent contrast-enhanced MRI and high resolution color Doppler and duplex ultrasonography of both sacroiliac joints (SIJ) for the detection of vascularization and blood flow spectral Doppler waveform analysis. MRI demonstrated active disease in 27 and inactive disease in 24 patients. CDUS detected pulsatile monophasic wave spectral waveform flow in 22 patients with the active disease, and triphasic in 7 patients with inactive disease and in 8 control patients. The sensitivity, specificity, positive predictive value and negative predictive value for active sacroiliitis detection with CDUS were 82 % (95 % CI, 68-91 %), 92 % (95 % CI, 85-96 %), 91 % (95 % CI, 84-96 %), and 84 % (95 % CI, 70-92 %), respectively, for pulsatile monophasic wave spe...Continue Reading

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Citations

Oct 16, 2013·Insights Into Imaging·Bernhard J Tins, Robin Butler
Apr 4, 2015·Annals of the Rheumatic Diseases·P MandlUNKNOWN European League Against Rheumatism (EULAR)
Dec 14, 2019·International Journal of Rheumatic Diseases·James Cheng-Chung WeiChung-Tei Chou
Nov 1, 2017·Rheumatology International·Marwin Gutierrez, Carlos Pineda
Aug 14, 2018·Rheumatology International·Marwin GutierrezCarlos Pineda
Dec 17, 2018·The Journal of Rheumatology·Javier E RosaEnrique R Soriano

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