Evaluation of donor's liver regeneration after left lobe harvesting for living-related liver transplantation

Transplantation Proceedings
R PaluszkiewiczM Krawczyk

Abstract

Computerized tomography-assisted volumetry permits one to estimate the volume of the liver graft as well as to monitor the regeneration in the donor for living- related liver transplantation (LRLT). The size of the whole liver and of the segments II, III, and IV was assessed in 64 living-related liver donors by preoperative computerized tomography (CT) volumetry. Segments II and III were harvested in 56 cases; segments II, III, and IV in 8 cases. The remnant liver was assessed by CT volumetry on postoperative days 7 and 30. There was a linear correlation between the calculated volume of the graft and its weight (R = 0.61, P < .04). Postoperative CT volumetry of the liver from a living-related donor showed a different pattern of volume restoration (regeneration index) both at 7 and 30 days among donors who sacrificed segments II and III versus segments II, III, and IV. The mean regeneration indices were significantly higher among donors of segments II, III, and IV compared with donors of segments II and III after 7 and 30 days (P < .05). It is possible that the donor liver displays a different pattern of growth due to the alteration in the blood supply to segment IV.

References

Nov 1, 1992·Annals of Surgery·M KobayashiT Hayashi
May 24, 1990·The New England Journal of Medicine·R W StrongG A Balderson
May 1, 1995·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K UrataM Makuuchi
Jul 1, 1993·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·N YamanakaW Tanaka
Jan 1, 1996·Transplant International : Official Journal of the European Society for Organ Transplantation·A TanakaY Yamaoka

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Citations

Jul 16, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·G Morris-StiffR Prasad

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