Evaluation of dry eye signs and symptoms in patients with systemic sclerosis.

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Beatriz de A F GomesHaroldo V Moraes

Abstract

One of the most frequent ocular features of systemic sclerosis (SSc) is dry eye disease (DED), which has been identified to occur in 37-79% of patients. Although several studies have found weak or no correlations between symptoms and signs of dry eye, symptoms are often the motivation for seeking eye care, and are therefore a critical outcome measure when assessing treatment effect. The aim of this study is to evaluate the impact of symptoms of dry eye on vision-related quality of life in patients with systemic sclerosis, and to investigate the relation between clinical tests and symptoms of dry eye in these patients. In this cross-sectional study, 45 consecutive patients with SSc were enrolled. For evaluation of the symptoms the "Ocular Surface Disease Index (OSDI)" questionnaire was applied to all patients. After that, all individuals were submitted to a full ophthalmic examination, including the following tests: tear break-up time, Schirmer I, rose bengal staining. Patients were then grouped into dry eye and non-dry eye groups with regard to the diagnosis of dry eye. Mann-Whitney test was used to compare continuous variables, whereas the Fisher exact test was used to compare categorical data between groups. Spearman's correl...Continue Reading

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Citations

Dec 24, 2015·International Ophthalmology·Sevinc Sahin AtikServet Akar
May 10, 2016·Current Eye Research·Murat GunayRahime Gul Yesiltepe Mutlu
Mar 21, 2015·Eye & Contact Lens·Beatriz A F GomesNewton Kara-Junior
Jul 15, 2015·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Hugo Pena-VerdealEva Yebra-Pimentel
Oct 3, 2019·Ocular Immunology and Inflammation·Gabriella SzucsAdam Kemeny-Beke

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