Evaluation of dual-energy subtraction of digital mammography images under conditions found in a commercial unit

Physics in Medicine and Biology
M E Brandan, V Ramírez-R

Abstract

Radiological contrast-to-noise ratio (CNR) is evaluated in subtracted images of microcalcifications in breast tissue. CNR is calculated for dual-kVp subtraction combining beams available in a Senographe 2000D, assuming single breast compression. Spectra were obtained from Boone et al (1997 Med. Phys. 24 1863-73), and the study was limited to lowest 25 kV Mo/Mo and highest 40 kV Rh/Rh beams, for 2.58 x 10(-4) C kg(-1) (1R) total exposure. For a standard case combining 25 kVp Mo/Mo and 40 kVp Rh/Rh beams, predicted maximum CNR for 300 microm calcification in 5 cm thick, 50% glandular, breast is about 1.2, below Rose's criterion for visualization. Total mean glandular doses are about 2.5 cGy for a standard case. The effect that input factors might have on predictions has been evaluated. Choice between alternative spectra can affect CNR by 50%. Assumed calcification composition leads to differences of 67% in calculated CNR, and assumed breast tissue composition can alter CNR by 45%; these results are weakly dependent on calcification or breast thickness, or on the assumed fraction of glandular tissue. CNR values are related to detected spectra effective energy. Calculations predict that above 37 kVp Mo/Mo beams are more energetic t...Continue Reading

References

Feb 1, 1979·Radiology·G R HammersteinJ S Laughlin
Jul 1, 1990·Medical Physics·J M BooneM Tecotzky
Nov 1, 1988·Radiology·A Fandos-MoreraA Traveria-Cros
Jan 1, 1989·Medical Physics·D P Chakraborty, G T Barnes
May 1, 1985·Medical Physics·P C JohnsA Fenster
Apr 20, 1999·Radiology·O H SuleimanF Houn
Jul 30, 2003·Physics in Medicine and Biology·A TaibiM Gambaccini
Apr 9, 2004·Medical Physics·Robert E AlvarezStephen K Thompson
Aug 13, 2004·Medical Physics·Arthur Burgess
Jun 1, 1985·Physics in Medicine and Biology·Robert F Wagner, David G Brown

❮ Previous
Next ❯

Citations

Sep 4, 2008·Physics in Medicine and Biology·S Cheenu Kappadath, Chris C Shaw
Oct 22, 2008·Physics in Medicine and Biology·Xuanqin MouLei Zhang
Dec 11, 2013·Medical Physics·Xi ChenXuanqin Mou
Jan 30, 2009·Medical Physics·Justin L Ducote, Sabee Molloi
Sep 18, 2013·IEEE Transactions on Medical Imaging·Seokmin Han, Dong-Goo Kang
Aug 8, 2015·Computational and Mathematical Methods in Medicine·V KoukouG Fountos
Apr 25, 2007·NMR in Biomedicine·Youssef Zaim WadghiriDavid E Gutstein
Aug 5, 2017·Physics in Medicine and Biology·N MartiniG Nikiforidis
Mar 27, 2013·Acta Radiologica·Chia-Jung TsaiJason J S Lee
Jun 18, 2016··María-Ester Brandan, María-Ester Brandan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.