Evaluation of fetal spine biometry between 11 and 14 weeks of gestation

Ultrasound in Medicine & Biology
Po-Jen ChengYung-Kuei Soong

Abstract

This study was designed to establish a fetal spine nomogram for age 11 through 14 weeks of gestation and to document relations among fetal spine length, distance and angle. These parameters were prospectively measured during the first trimester of singleton pregnancies, along with nuchal translucency, over a 3-year period. A total of 430 fetuses were included in the study. The regression equations among fetal spine parameters and gestational age were as follows: Spine length (mm) = 1.116 x gestational age (days) - 59.169; spine distance (mm) = 1.079 x gestational age (days) - 59.038; head-spine angle = 0.740 x gestational age (days) + 4.735; spine length:spine distance ratio = -0.002 x gestational age (days) + 1.234. Prenatal age-specific reference intervals for fetal spine biometry between 11 and 14 weeks of gestation may assist in evaluation of fetuses investigated for genetic abnormalities that can be expressed by deviation in spine length, distance, or angle.

References

Jun 1, 1981·Acta Orthopaedica Scandinavica·T Tanaka, H K Uhthoff
Apr 16, 1999·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·Y H LamJ M Nicholls
Sep 12, 2002·Prenatal Diagnosis·P De BiasioG Aicardi
Dec 9, 2004·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A P SoukaA Antsaklis
May 3, 2005·Obstetrics and Gynecology·Po-Jen ChengYung-Kuei Soong
May 20, 2005·Reproductive Biomedicine Online·Boaz WeiszEric Jauniaux
Sep 15, 2005·American Journal of Obstetrics and Gynecology·Fionnuala M McAuliffeJo-Ann Johnson
May 16, 2006·Journal of the Society for Gynecologic Investigation·Po-Jen ChengYung-Kuei Soong
Sep 27, 2008·Fetal Diagnosis and Therapy·Po-Jen ChengYung-Kwei Soong

❮ Previous
Next ❯

Citations

Feb 12, 2013·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Cindy ShuJames Melrose

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Aphasia

Aphasia affects the ability to process language, including formulation and comprehension of language and speech, as well as the ability to read or write. Here is the latest research on aphasia.