Evaluation of fine needle aspiration cytology in the diagnosis of cervical lymph node lymphomas

Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery
Yoldez HoucineSoumaya Rammeh

Abstract

Surgical biopsy examination is the gold standard for the diagnosis of lymph node lymphomas. Fine-needle aspiration cytology (FNAC) is a quick and safe method in the management of cervical lymph nodes. Its value in confirming recurrent or residual lymphoma is well established. However, its role in the primary diagnosis of lymph node lymphoma remains controversial. The aim of this study was to assess, in our experience, the reliability of FNAC in the diagnosis of cervical lymph node lymphomas. This was a retrospective study carried out over a 6-year period (January 2011 to December 2016) and conducted at the Cytology Unit in our Pathology Department (Charles Nicolle Hospital, Tunisia). The measures of diagnostic accuracy of FNAC in the diagnosis of cervical lymph node lymphomas were calculated taking histopathology as the gold standard. A total of 937 FNA samples were obtained from 851 patients. The diagnosis of lymphoma was obtained in 65 cases (6.9%). Cytological diagnoses of lymphoma were as follows: 28 (44%) Hodgkin lymphoma, 17 (25%) high-grade lymphoma, 15 (23%) low-grade lymphoma, and 5 (8%) "suggestive of lymphoma." FNAC of cervical lymph nodes had a sensitivity of 95.5%, specificity of 98.7%, positive predictive value (P...Continue Reading

Citations

Aug 1, 2019·American Journal of Clinical Pathology·Kimberly F IngersollEndi Wang
Jul 19, 2020·Cytopathology : Official Journal of the British Society for Clinical Cytology·Maria Eduarda Pérez-de-OliveiraPablo Agustin Vargas
Nov 22, 2020·American Journal of Clinical Pathology·Steven H KroftMatthew C Cheung
Sep 17, 2021·Cytopathology : Official Journal of the British Society for Clinical Cytology·Adriana Passos BuenoMauro Ajaj Saieg
Dec 4, 2021·The British Journal of Radiology·Katharine Julia HurryDavid C Howlett

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