PMID: 6986948Feb 2, 1980Paper

Evaluation of flurbiprofen in detrusor instability

British Medical Journal
L CardozoD Hole

Abstract

Thirty women with detrusor instability (27 cases idiopathic, and three secondary to multiple sclerosis) completed a double-blind, cross-over trial of the prostaglandin synthetase inhibitor flurbiprofen and a placebo, results being evaluated by questionnaire and cystometry. Frequency, urgency, and urge incontinence were all significantly reduced with flurbiprofen (P less than 0.001, P less than 0.025, and P less than 0.025 respectively), as was the detrusor-pressure rise during bladder filling (P less than 0.01). Side effects, however, occurred in 13 patients while taking flurbiprofen compared with five while taking placebo (P less than 0.025). After the trial 19 patients wished to continue with flurbiprofen. Flurbiprofen is a useful treatment for idiopathic detrusor instability and is well tolerated by most patients.

References

Jun 1, 1979·British Journal of Urology·L D CardozoJ E Williams
Jan 1, 1975·British Journal of Urology·P H Abrams, R C Feneley
Jan 1, 1971·The British Journal of Radiology·C P Bates, C E Corney
Mar 1, 1980·British Journal of Obstetrics and Gynaecology·L D Cardozo, S L Stanton

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Citations

Jan 1, 1997·International Urogynecology Journal and Pelvic Floor Dysfunction·S ShimonovitzS L Stanton
Nov 9, 2002·Obstetrics and Gynecology·Guenther HaeuslerClemens B Tempfer
May 14, 1983·Lancet
May 14, 1983·Lancet
Jun 19, 2002·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Roberto PregazziSecondo Guaschino
Nov 1, 1991·Journal of Internal Medicine·V FossaluzzaS De Vita
Nov 15, 1980·British Medical Journal·G J Jarvis, D R Millar
Feb 28, 2014·Biomedical Research·Yumiko FukiyaMasahito Kawatani
Mar 1, 2006·Women's Health·Dudley Robinson, Linda Cardozo
Mar 2, 2010·Women's Health·Monika VijLinda Cardozo
May 1, 2008·Current Prostate Reports·Jennifer L St Sauver, Steven J Jacobsen
Jul 28, 2013·Expert Opinion on Emerging Drugs·Eu Kiang Sharon YeoPaul Abrams
Sep 4, 2008·Expert Opinion on Emerging Drugs·Marcus J Drake
Feb 9, 2011·Expert Opinion on Pharmacotherapy·Anastasios Athanasopoulos, Francisco Cruz
Sep 12, 2015·Expert Opinion on Emerging Drugs·Roopali Karmarkar, Vik Khullar
Dec 1, 1990·Annals of Medicine·G Lose
Oct 23, 1997·The American Journal of the Medical Sciences·P S Goode, K L Burgio
Sep 18, 2009·The Journal of Urology·Karl-Erik Andersson
Dec 7, 2011·International Journal of Urology : Official Journal of the Japanese Urological Association·Keisuke YamamotoNorio Nonomura
Dec 22, 2009·Neurourology and Urodynamics·Karl-Erik Andersson
Dec 1, 1984·Controlled Clinical Trials·C L MeinertK Higgins
Aug 8, 1981·Lancet·J H PalmerA N Exton-Smith
Jun 1, 1982·British Journal of Clinical Pharmacology·J M Robinson
Dec 1, 1980·British Journal of Urology·D D Elder, T P Stephenson
Mar 1, 1990·Journal of the American Geriatrics Society·A J Wein
Jul 18, 2000·Baillière's Best Practice & Research. Clinical Obstetrics & Gynaecology·K E Andersson
Aug 24, 2004·Journal of Pharmacological Sciences·Hiroko Takagi-MatsumotoMasaomi Tajimi
Apr 27, 2017·Neurourology and Urodynamics·Marcus J DrakeJulian R Marchesi
Aug 19, 2007·Neurourology and Urodynamics·K-E Andersson
Mar 14, 2012·Nature Reviews. Urology·Mohammad S Rahnama'iGommert A van Koeveringe
Jan 1, 2008·Expert Review of Clinical Pharmacology·Dudley Robinson, Linda Cardozo
May 19, 2009·Current Opinion in Urology·Karl-Erik AnderssonAlan J Wein
Jul 1, 1988·Drug Intelligence & Clinical Pharmacy·G L RomanowskiM I Cahn
Oct 1, 1988·Drug Intelligence & Clinical Pharmacy·L A ShimpG L Gillis
May 1, 1983·The Journal of Urology·P KlarskovT Hald
Jun 1, 1989·British Journal of Obstetrics and Gynaecology·L L Wall, D W Warrell
Nov 26, 1999·BJU International·K E AnderssonR Vela Navarrete
Jan 25, 2005·BJOG : an International Journal of Obstetrics and Gynaecology·P Toozs-Hobson, A Elnaqa

❮ Previous
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