Evaluation of focal retinal function using multifocal electroretinography in patients with X-linked retinoschisis

Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
Parveen SenPriya Ravi

Abstract

To evaluate focal retinal function in patients presenting with features of X-linked retinoschisis (XLRS), with the use of multifocal electroretinography (mfERG). Consecutive observational case-control study. Eighteen eyes of 9 patients who presented to the retina clinic of Sankara Nethralaya from 2005 to 2008. XLRS was diagnosed clinically and corroborated with full-field electroretinogram (ffERG), mfERG, and optical coherence tomography. ffERG and mfERG recordings were done with VERIS 5.2.2X according to International Society for Clinical Electrophysiology of Vision standards. The mfERG stimulus consisted of 103 hexagons flickered at a 75 Hz frame rate, subtended 35° horizontally and 31° vertically at a viewing distance of 53 cm. The amplitudes and implicit times of ffERG and first-order kernels of mfERG were analyzed and compared with those of the controls. P1 and N1 amplitudes were reduced and P1 and N1 implicit times were prolonged significantly in patients with XLRS, compared with controls. mfERG helps estimate focal retinal function in patients with XLRS.

References

Apr 1, 1987·Archives of Ophthalmology·N S PeacheyM G Brigell
Aug 1, 1972·Archives of Ophthalmology·W A Manschot
Jan 1, 1968·Archives of Ophthalmology·M YanoffL E Zimmerman
Mar 1, 1996·Archives of Ophthalmology·N D GeorgeA T Moore
Jul 31, 1998·Protein Science : a Publication of the Protein Society·S BaumgartnerP Bucher
Oct 28, 2003·Investigative Ophthalmology & Visual Science·Chang-Hua PiaoYozo Miyake
Feb 14, 2007·Archives of Ophthalmology·Stephen H TsangGraham E Holder
Jan 1, 1938·The British Journal of Ophthalmology·I Mann, A Macrae

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Citations

Jul 4, 2012·International Ophthalmology·Sungeun E Kyung, Minsoo Lee
Jun 25, 2013·Documenta Ophthalmologica. Advances in Ophthalmology·Richard E SteadChea S Lim
May 9, 2012·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Fatih C GundoganOmer Faruk Sahin
Jan 17, 2012·Progress in Retinal and Eye Research·Robert S MoldayBernhard H F Weber
Sep 1, 2021·Eye·Sangeetha Srinivasan Muna Bhende

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