PMID: 15386973Sep 25, 2004Paper

Evaluation of fracture toughness of cartilage by micropenetration

Journal of Materials Science. Materials in Medicine
N K SimhaJ L Lewis

Abstract

Failure properties of cartilage are important in injury repair and disease, but few methods exist for measuring these properties, especially in small animals. To meet this need, a new indentation/penetration method for measuring fracture toughness of cartilage is proposed. During indentation, a conical tip is displaced into the surface of the cartilage, causing first a non-penetrating indentation, and then a penetration into the tissue. The method assumes that tissue penetration occurs during periods of "rapid work", which are identified from a curve of work rate vs. time. Total penetration depth is determined by summing the displacement during these periods. Fracture work is the work that occurs during "rapid work", or penetration, and fracture toughness defined as the fracture work divided by one-half the penetrated surface area of the indenting tip. The method was validated by indentation testing of bovine cartilage. Penetrating indentations with a conical tip were performed in bovine patellar cartilage and depth of penetration and fracture toughness predicted. For comparison with the indentation data, depth of penetration was measured in histological sections. These measurements agreed well with the predicted depth. Predict...Continue Reading

Citations

Sep 8, 2012·Nature·Jeong-Yun SunZhigang Suo
Mar 2, 2013·Tissue Engineering. Part B, Reviews·Yinghua XiaoMichael S Detamore
Feb 4, 2014·Chemistry of Materials : a Publication of the American Chemical Society·Hao BaiAntoni P Tomsia
Jul 25, 2009·Journal of the Mechanical Behavior of Biomedical Materials·Y L ChanN M King
Mar 17, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Ali A MohammedJulian R Jones
Nov 4, 2016·Advanced Materials·Danielle Lynne Taylor, Marc In Het Panhuis
Jul 18, 2020·Scientific Reports·Yujing YouZhiqiang Jiang
May 8, 2018·Journal of Biomechanics·Joseph E PichamuthuDavid A Vorp
May 7, 2021·Advanced Materials·Zhenwei MaJianyu Li

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