Evaluation of frequently used drug interaction screening programs.

Pharmacy World & Science : PWS
Priska VonbachJürg H Beer

Abstract

Drug-drug interaction (DDI) screening programs are an important tool to check prescriptions of multiple drugs. The objective of the current study was to critically appraise several DDI screening programs. A DDI screening program had to fulfil minimal requirements (information on effect, severity rating, clinical management, mechanism and literature) to be included into the final evaluation. The 100 most frequently used drugs in the State Hospital of Baden, Switzerland, were used to test the comprehensiveness of the programs. Qualitative criteria were used for the assessment of the DDI monographs. In a precision analysis, 30 drugs with and 30 drugs without DDIs of clinical importance were tested. In addition, 16 medical patient profiles were checked for DDIs, using Stockley's Drug Interactions as a reference. Suitability of DDI screening program (quality of monographs, comprehensiveness of drug list, statistical evaluation). Out of nine programs included, the following four fulfilled the above mentioned criteria: Drug Interaction Facts, Drug-Reax, Lexi-Interact and Pharmavista. Drug Interaction Facts contained the smallest number of drugs and was therefore the least qualified program. Lexi-Interact condenses many DDIs into one g...Continue Reading

References

Jul 1, 1993·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·C A Jankel, L K Fitterman
Jul 1, 1993·The Annals of Pharmacotherapy·T R Einarson
Apr 29, 1998·JAMA : the Journal of the American Medical Association·J LazarouP N Corey
Apr 12, 2001·Journal of the American Pharmaceutical Association : APhA·P D HanstenT K Hazlet
Apr 12, 2001·Journal of the American Pharmaceutical Association : APhA·T K HazletJ R Horn
Jun 27, 2001·International Journal of Impotence Research·S L MerlinS B Dion
Sep 5, 2002·Journal of Pharmaceutical Sciences·Caiping Yao, René H Levy
Oct 18, 2002·Journal of Clinical Pharmacy and Therapeutics·D MagnusA J Avery
Nov 26, 2003·Archives of Internal Medicine·Saul N WeingartRussell S Phillips
Mar 12, 2004·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Robert Barrons
Apr 22, 2004·Journal of the American Pharmacists Association : JAPhA·Jacob AbarcaRichard B Lipton
Jul 3, 2004·BMJ : British Medical Journal·Munir PirmohamedAlasdair M Breckenridge

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Citations

Jun 7, 2013·European Journal of Clinical Pharmacology·Srecko MarusicNives Gojo-Tomic
Apr 17, 2013·Cancer Chemotherapy and Pharmacology·Molouk HadjibabaieArdeshir Ghavamzadeh
Jan 16, 2010·Pharmacy World & Science : PWS·Anna ChatsisviliIoannis Niopas
Feb 6, 2010·Pharmacy World & Science : PWS·F LapiA Vannacci
Jun 18, 2010·Pharmacy World & Science : PWS·Isabella De GiorgiPascal Bonnabry
Oct 22, 2010·Pharmacy World & Science : PWS·Adriano Max Moreira Reis, Silvia Helena De Bortoli Cassiani
Mar 29, 2011·International Journal of Clinical Pharmacy·Melanie Isabelle Brulhart, Joel Pierre Wermeille
Oct 14, 2011·International Journal of Clinical Pharmacy·Rosimeire Barbosa Fonseca GuastaldiSilvia Regina Secoli
Jul 3, 2013·International Journal of Clinical Pharmacy·Cheng Kin LaoAlexandre Chan
Jun 27, 2014·Daru : Journal of Faculty of Pharmacy, Tehran University of Medical Sciences·Ehsan NabovatiSaeid Eslami
Feb 25, 2014·International Journal of Clinical Pharmacy·Anna VéghLajos Botz
Jul 16, 2013·International Journal of Clinical Pharmacy·Thomas FißWolfgang Hoffmann
May 31, 2012·European Journal of Clinical Pharmacology·Paulo Roque Obreli-NetoRoberto Kenji Nakamura Cuman
Mar 16, 2013·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Olesya I ZorinaStefan Russmann
Jan 6, 2015·Expert Opinion on Drug Metabolism & Toxicology·Maryam FarhoudiLadan Abbasian
Jan 23, 2016·European Journal of Clinical Pharmacology·Michele ThaiDanijela Gnjidic
Apr 5, 2011·Clinical Therapeutics·Frank G A JansmanUNKNOWN Dutch Society of Clinical Pharmacology and Biopharmacy (NVKF&B)
Mar 23, 2010·Medicina clínica·Paloma Villacorta LinazaMaría de la O Caraballo Camacho
Oct 14, 2008·European Journal of Internal Medicine·Priska VonbachJürg H Beer
Apr 21, 2012·Pharmacoepidemiology and Drug Safety·Olesya I ZorinaStefan Russmann
Feb 26, 2015·International Journal of Clinical Pharmacy·Paula Stoll, Luciane Kopittke
Dec 23, 2014·European Journal of Clinical Pharmacology·Tina RoblekMitja Lainscak
Mar 10, 2016·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Dingwei DaiChris Feudtner
Jul 25, 2013·Chemotherapy·A MouzonA Spinewine
Dec 17, 2009·São Paulo Medical Journal = Revista Paulista De Medicina·Genici Weyh BleichJorge Juarez Vieira Teixeira
Dec 31, 2009·The Annals of Pharmacotherapy·Lorraine M WangChristine M Cheng
Dec 20, 2017·European Journal of Clinical Pharmacology·Camille MorivalPascal Le Corre
Aug 22, 2017·International Journal of Clinical Pharmacy·Julia AmkreutzAlbrecht Eisert
Sep 12, 2017·Journal of Psychiatric and Mental Health Nursing·E C D CastilhoA I Miasso
Jan 18, 2018·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·Walter E Haefeli, Hanna M Seidling
Jan 31, 2019·Ciência & saúde coletiva·Ronara Camila de Souza Groia VelosoAdriano Max Moreira Reis
Dec 12, 2018·Journal of Pediatric Hematology/oncology·Faezeh TavousiAzadeh Moghaddas
May 16, 2019·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Lea D BrühwilerMonika Lutters
Dec 4, 2019·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·O O Kirilochev, A R Umerova
Dec 5, 2017·European Journal of Clinical Pharmacology·Ylva BöttigerMarine L Andersson

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