Evaluation of gastric antral motor performance in patients with dysmotility-like dyspepsia using real-time high-resolution ultrasound

Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society
N K AhluwaliaJ Hindle

Abstract

Although manometric antral hypomotility and delayed gastric emptying have been reported separately in patients with dyspepsia, relationships between symptoms, antral contractility and emptying rate have not been sought. The present study therefore aimed to evaluate, simultaneously, gastric antral excursion characteristics and emptying in a sub-group of patients with severe functional dyspepsia using high-resolution real-time ultrasound. The circumference of the relaxed and contracted antrum was measured at 15-min intervals after ingestion of a 360 mL mixed nutrient meal in 36 chronic dyspepsia patients with symptoms of post-prandial bloating and epigastric distension, and in 25 healthy volunteers. Antral emptying (measured as the rate of decrease in circumference of the relaxed antrum) was slower in patients than normals (P = 0.02). In both groups, the average values for antral excursion were similar but the range of excursion in patients was significantly wider than in controls (F < 0.001), with 11 patients showing values above, and 8 showing values below the normal range. There was no relationship between antral emptying and antral excursion in either patients or volunteers. In conclusion, patients with severe functional dysp...Continue Reading

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Citations

May 17, 2001·Current Gastroenterology Reports·N J Talley, S Thitiphuree
Feb 1, 1997·Alimentary Pharmacology & Therapeutics·E OkamotoG Kajiyama
Dec 1, 1996·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·E M Quigley
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Mar 27, 2009·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Telma V Moreira, Margaret McQuiggan
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Jul 18, 2002·American Journal of Physiology. Gastrointestinal and Liver Physiology·H GregersenA Berstad
Dec 23, 2003·The American Journal of Gastroenterology·Christine Feinle-BissetNicholas J Talley
Jan 13, 2021·Physiological Measurement·Elisabeth K SteinsvikOdd Helge Gilja
Jun 10, 2021·Ultrasound International Open·Giovanni MaconiOdd Helge Gilja

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