Evaluation of glucose dose on intravenous glucose tolerance test traits in Holstein-Friesian heifers

Journal of Dairy Science
L Antonio González-GrajalesRudolf Staufenbiel

Abstract

Glucose metabolism in dairy and beef cattle has received considerable attention because balanced blood glucose is essential for numerous processes, such as milk production and general health. The glucose tolerance test measures the ability of an organism to regulate blood glucose levels. Glucose half-life time (GHLT) has high heritability and could serve as a potential parameter to breed for metabolic resistance. However, studies focusing on identification of an adequate glucose dose have not yet been conducted in cattle. The objective of this study was to analyze the effect of 5 different glucose doses (0.5, 1, 1.5, 2, and 3 g/kg of body weight0.75) on intravenous glucose tolerance test (ivGTT) traits and insulin responses in nongestating heifers. A total of 150 tests were performed in 30 Holstein-Friesian heifers aged 13 to 15 mo. Blood samples were obtained every 7 min after glucose injection until min 63. Glucose traits and insulin parameters included blood serum glucose and insulin concentration at min 0 (basal concentration), min 7 to 21 (peak glucose and insulin concentration), and min 63 (last sampling) relative to glucose administration, glucose and insulin area under the curve (GAUC and IAUC), and GHLT estimated betwe...Continue Reading

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Citations

Jan 7, 2019·Acta Veterinaria Scandinavica·Leslie Antonio González-GrajalesRudolf Staufenbiel
Dec 12, 2019·Tropical Animal Health and Production·Aliasghar ChalmehMohammad Mazrouei Sebdani
Feb 5, 2019·Journal of Dairy Science·L Antonio González-GrajalesRudolf Staufenbiel
Dec 8, 2020·Frontiers in Cell and Developmental Biology·Xin WenCheng-Guang Liang

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