PMID: 6990948Jan 1, 1980Paper

Evaluation of glycopyrrolate and atropine as adjuncts to reversal of non-depolarizing neuromuscular blocking agents in a "true-to-life" situation

British Journal of Anaesthesia
D A CozanitisR K Mirakhur

Abstract

Glycopyrrolate, a quaternary ammonium anticholinergic compound, and atropine were evaluated in combination with neostigmine for antagonism of non-depolarizing neuromuscular block. A total of 641 patients were investigated in a "true-to-life" situation. The patients receiving glycopyrrolate with neostigmine had smaller changes in heart rate than those who received atropine. This was particularly apparent in patients with cardiovascular disease.

Citations

Jan 1, 1981·General Pharmacology·R K Mirakhur, J W Dundee
Jul 1, 1993·Acta Anaesthesiologica Scandinavica·H GrønnebechN Valentin
Oct 1, 1993·Acta Anaesthesiologica Scandinavica·T Ali-MelkkiläE Iisalo
Dec 19, 2013·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Jinyoung HwangJin Huh
Sep 1, 1988·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·R K Mirakhur
Mar 11, 2009·Journal of Critical Care·James E Caldwell
Feb 19, 2009·Anaesthesia·J E Caldwell, R D Miller
Feb 19, 2009·Anaesthesia·R K Mirakhur
Dec 1, 1983·Anaesthesia·R K Mirakhur, J W Dundee
Aug 1, 1984·Acta Anaesthesiologica Scandinavica·O TakkunenJ Heinonen
Feb 1, 1981·Anaesthesia·W P BlunnieP D McIlroy
Apr 1, 1982·Acta Anaesthesiologica Scandinavica·J HeinonenO Takkunen
Jan 1, 1982·Anaesthesia·D A CozanitisA Kauste
Jun 4, 2016·Veterinary Anaesthesia and Analgesia·Manuel Martin-FloresGabriela E Aguirre
Dec 1, 1982·Acta Anaesthesiologica Scandinavica·F Kongsrud, S Sponheim
May 1, 1986·Acta Anaesthesiologica Scandinavica·F MogensenN Valentin
Jan 1, 1987·Fundamental & Clinical Pharmacology·F A WaliC H Dark
Nov 1, 1983·British Journal of Clinical Pharmacology·D Preiss, P Berguson

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