Evaluation of Hypocaloric Diet With Protein Supplementation in Middle-Aged Sarcopenic Obese Women: A Pilot Study

Obesity Facts
Rosa SammarcoFabrizio Pasanisi

Abstract

The aim of this study was to evaluate the efficacy of a nutritional program, which is characterized by a different modulation of proteins, in adult patients with sarcopenic obesity. We studied 18 obese women aged 41-74 years. Obesity was diagnosed as fat mass > 34.8% and sarcopenia was defined when lean body mass was <90% of the subject's ideal fat free mass. All subjects were randomly assigned to different nutritional interventions: Hypocaloric diet plus placebo (A) and hypocaloric high-protein diet (1.2-1.4 g / kg body weight reference / day) (B). Anthropometric measurements, body composition, resting energy expenditure, handgrip test, Short Physical Performance Battery (SPPB), and SF-36 questionnaire were evaluated at baseline and after 4 months. Weight significantly decreased in both groups. Women with high-protein diet preserved lean body mass compared to low-calorie diet and improved significantly muscle strength; SPPB score did not change in both groups. SF-36 test showed a significant change for general health after 4 months in group B. In our study, sarcopenic obese patients with high-protein diet showed an improvement in muscle strength. Furthermore, dietary protein enrichment may represent a protection from the risk ...Continue Reading

References

Oct 1, 1993·Health Economics·R D HaysR M Mazel
Apr 29, 1998·American Journal of Epidemiology·R N BaumgartnerR D Lindeman
Feb 11, 2004·American Journal of Epidemiology·Ian JanssenRonenn Roubenoff
Jul 26, 2005·Physiology & Behavior·Annemiek M C P JoosenKlaas R Westerterp
Apr 6, 2006·JAMA : the Journal of the American Medical Association·Cynthia L OgdenKatherine M Flegal
Apr 9, 2008·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Mauro ZamboniVincenzo Di Francesco
Apr 16, 2009·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Jung Sun LeeUNKNOWN Health ABC Study
Apr 16, 2010·Age and Ageing·Alfonso J Cruz-JentoftUNKNOWN European Working Group on Sarcopenia in Older People
May 25, 2010·Current Opinion in Clinical Nutrition and Metabolic Care·Girish KewalramaniAmira Klip
Nov 3, 2010·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Kristina NormanMatthias Pirlich
May 26, 2012·Frontiers in Physiology·Gregory C Bogdanis
Jul 20, 2012·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·C M M PradoM Siervo

❮ Previous
Next ❯

Citations

Aug 2, 2018·Nature Reviews. Endocrinology·John A Batsis, Dennis T Villareal
Nov 22, 2018·Current Opinion in Clinical Nutrition and Metabolic Care·Mauro ZamboniAndrea P Rossi
Nov 16, 2019·Nature Reviews. Endocrinology·Bettina MittendorferLuigi Fontana
Sep 29, 2020·Frontiers in Endocrinology·Mina WangPeng Wei
Jun 12, 2019·Nutrients·Maria L PetroniGiulio Marchesini
Jul 17, 2019·Experimental Biology and Medicine·Maysa Vieira de SousaRonaldo Cardoso
Aug 11, 2021·Nutrients·David McCarthy, Aloys Berg

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.