PMID: 8601319Apr 1, 1996Paper

Evaluation of i-STAT portable clinical analyzer in a hemodialysis unit

Clinical Biochemistry
M H Gault, C E Harding

Abstract

To evaluate a hand held portable i-STAT analyzer used for point-of-care testing in a hemodialysis unit. Imprecision and comparison studies. Assays by nonlaboratory personnel. Study of both quality control solutions and hemodialysis patients' duplicate blood specimens with 6+, E3+, EC6+, and EC8+ cartridges both gave CVs for sodium, potassium, chloride, pH, and ionized calcium of 0 to 2.2%. CVs for hematocrit, glucose and pCO2 for whole blood duplicates were 4.6, 3.5, and 4.0%. The mean differences between i-STAT and central laboratory values for the above compounds and urea, when expressed as a % of mean central laboratory values were 0.2 and 3.1%, except for an ionized calcium value of 4.3% (for which there is an explanation) and for glucose (11%) that were both higher for i-STAT. Preliminary data suggest that sodium, potassium, ionized calcium, and pH can be assayed in the aqueous dialysate fluid used for hemodialysis. We confirm previous reports that i-STAT cartridges give simple, rapid, and reliable values for sodium, potassium, chloride, urea, glucose, and hematocrit that are clinically acceptable when performed by nonlaboratorians, but also suggest the same conclusions apply to ionized calcium, pH, and pCO2. The hemodialy...Continue Reading

References

Dec 1, 1993·American Journal of Clinical Pathology·J WooJ B Henry

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Citations

Jul 13, 2002·The Journal of Emergency Medicine·Gregory J Fermann, Joe Suyama
Sep 28, 1999·The Journal of Emergency Medicine·R P MurrayL Ludwig
Apr 4, 2000·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·G M KiebzakZ Y Zhang
Dec 19, 2006·Journal of the American Veterinary Medical Association·René A VarelaGregory D Bossart
Oct 11, 2007·Clinical Chemistry and Laboratory Medicine : CCLM·Paul W SchenkYolanda B de Rijke
Jul 19, 2006·Journal of Science and Medicine in Sport·B J DascombeA J Coutts
Sep 23, 2016·Expert Review of Medical Devices·Manoj K SharmaJeroen P Kooman
Aug 22, 2014·Journal of Veterinary Emergency and Critical Care·Carlos TorrenteRafael Ruiz de Gopegui
Jun 15, 1997·Analytical Chemistry·D J AndersonK A Davis

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