Evaluation of iQ200 automated urine microscopy analyzer

The Korean journal of laboratory medicine
Joowon Park, Jongwan Kim

Abstract

Microscopic examination of urine sediment is one of the most commonly performed tests in the clinical laboratory. However, manual microscopic sediment examination is labor-intensive, time-consuming and imprecise. In this study, we evaluated the analytical performance and clinical usefulness of a recently introduced image-based automated urinalysis system, Iris iQ200 (Iris Diagnostics, USA). We assessed the iQ200 for linearity, precision and carryover rate using patient's samples and quality control materials. On 337 urine samples, urine sediment analyses performed by the iQ200 were compared with manual microscopy results. The iQ200 showed a good linearity (r2>0.99) for all cellular components analyzed. Within-run and total CVs on urine specimens and quality control samples were less than 10% except for within-run CV for the samples with low concentration of the squamous epithelial cells. The carryover rates were 0.21% for RBCs and 1.92% for WBCs. The agreement rates within one grade between the iQ200 and manual microscopy for RBCs, WBCs, and squamous epithelial cells were 93.8%, 94.2% and 96.9%, respectively. Since the iQ200 showed a reliable analytical performance and good concordance with manual microscopy, it could be useful...Continue Reading

References

Nov 1, 1986·American Journal of Clinical Pathology·C E RoeB E Statland
Dec 1, 1986·American Journal of Clinical Pathology·R J ElinH H Nishi
Apr 11, 2001·American Journal of Clinical Pathology·H OkadaS Kamidono
May 22, 2003·Journal of the American Geriatrics Society·UNKNOWN AGS Clinical Practice Committee
Jun 10, 2003·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Stanton D Harn, Timothy M Durham
Jul 16, 2005·Clinica Chimica Acta; International Journal of Clinical Chemistry·Pornvaree LamchiagdhaseBoonsong Preechaborisutkul
Jul 3, 2007·Clinica Chimica Acta; International Journal of Clinical Chemistry·Tzu-I ChienMiao-Ju Chien

❮ Previous
Next ❯

Citations

Jul 21, 2015·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Mohamed Abdel-Salam El-GuindiAhmad Mohamed Sira
Nov 23, 2013·The Pediatric Infectious Disease Journal·Ami P ShahRobert W Hickey
Oct 31, 2019·Scandinavian Journal of Clinical and Laboratory Investigation·Rui ZhangQingtao Wang
Sep 15, 2018·Annals of Laboratory Medicine·Matthijs Oyaert, Joris Delanghe
Oct 4, 2020·Laboratory Medicine·Vani ChandrashekarVikram Prabhakar

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinica Chimica Acta; International Journal of Clinical Chemistry
Tzu-I ChienMiao-Ju Chien
Clinica Chimica Acta; International Journal of Clinical Chemistry
Pornvaree LamchiagdhaseBoonsong Preechaborisutkul
Clinical Chemistry and Laboratory Medicine : CCLM
Peter HoffmannMathias Zimmermann
© 2022 Meta ULC. All rights reserved