Evaluation of left ventricular ejection fraction by the quantitative algorithms QGS, ECTb, LMC and LVGTF using gated myocardial perfusion SPECT: investigation of relative accuracy

Nuclear Medicine Communications
Magdy M KhalilWafaa Khalil

Abstract

To compare the quantitative algorithms Emory Cardiac Toolbox (ECTb), quantitative gated SPECT (QGS), layer of maximum counts (LMC), and left ventricular global thickening fraction (LVGTF) using gated myocardial tomography in the calculation of the left ventricular ejection fraction using the regression without truth (RWT) technique. Seventy-four consecutive patients were included in the study (59 males). All patients underwent stress-rest myocardial perfusion SPECT using Tc-tetrofosmin. Analysis of variance (ANOVA), the paired Student's t-test, the Pearson correlation coefficient and Bland-Altman were used for comparing the methods. The relative accuracy was performed by RWT. ANOVA revealed a significant difference among the methods in calculating the ejection fraction. RWT showed that ECTb and QGS outperformed the other two methods. The ECTb was slightly better than QGS, and LMC was slightly better than LVGTF. QGS and ECTb achieved good correlations in end diastolic volume, end systolic volume and ejection fraction measurements. One-way ANOVA demonstrated that QGS was the only software program affected by the category of the perfusion summed stress score (SSS), P=0.038. The ejection fraction determined by the QGS, ECTb and LVG...Continue Reading

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Citations

Apr 21, 2009·European Journal of Nuclear Medicine and Molecular Imaging·Feng WangZuo-Xiang He
Jul 22, 2009·International Journal of Technology Assessment in Health Care·Edwina AdamsBarbara Adamson
Mar 14, 2009·Nuclear Medicine Communications·Frances M LavenderKuldip S Nijran
Apr 10, 2014·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Sameer AtherFadi G Hage
Aug 21, 2019·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Patrycja Galazka, Steven Port
Oct 18, 2020·Annals of Nuclear Medicine·Osama S HanafyHaitham S Mohammed
May 21, 2010·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Paco E BravoFrank M Bengel

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