PMID: 9177876Mar 1, 1997Paper

Evaluation of lipid peroxidation and total antioxidant status in plasma of rats following thermal injury

Burns : Journal of the International Society for Burn Injuries
O CetinkaleT Tas

Abstract

Thermal injury initiates systemic inflammatory reactions producing burn toxins, an inflammatory response, oxygen radicals and finally peroxidation. The relationship between the amount of products of oxidative metabolism and natural scavengers of free radicals determines the outcome of local and distant tissue damage, and further organ failure in burn injury. To determine the relationship between the level of total natural scavengers of the body, the place of superoxide dismutase in this capacity, and its relation with lipid peroxidation, malondialdehyde, superoxide dismutase levels and total antioxidant status were measured in plasma. Animals were subjected to 30 per cent full thickness body surface area burn, and their blood was collected at 24 h postburn. Plasma malondialdehyde levels were significantly elevated above the level of controls (P < 0.02). Burn injury caused a remarkable decrease in superoxide dismutase (45 per cent decrease, P < 0.0001) and total antioxidant status (14 per cent decrease, P < 0.01) when compared to control.

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Citations

Mar 17, 2004·Burns : Journal of the International Society for Burn Injuries·Mübin HoşnuterAhmet Işikdemir
Jun 7, 2005·Burns : Journal of the International Society for Burn Injuries·Göksel SenerBerrak C Yeğen
May 14, 2005·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Levent KabasakalBerrak C Yeğen
Jul 26, 2002·Life Sciences·Göksel SenerBerrak C Yeğen
May 12, 2001·Burns : Journal of the International Society for Burn Injuries·B Latha, M Babu
Aug 30, 2001·Burns : Journal of the International Society for Burn Injuries·D SaitohY Okada
Mar 5, 2003·Burns : Journal of the International Society for Burn Injuries·Yoshitaka GotohYoshiaki Okada
May 6, 1998·Burns : Journal of the International Society for Burn Injuries·J W HaycockS MacNeil
Oct 17, 1998·Burns : Journal of the International Society for Burn Injuries·B LathaM Babu
Mar 31, 2000·Burns : Journal of the International Society for Burn Injuries·A RawlingsonS D Brain
May 23, 2001·Pathologie-biologie·M FarriolT Segovia
Apr 20, 2004·The Journal of Burn Care & Rehabilitation·Ferah ArmutcuCevdet Altnyazar
Nov 10, 2005·The Journal of Burn Care & Rehabilitation·Abdullah SakarcanGöksel Sener
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Jul 8, 2000·Free Radical Research·A M PintaudiM A Livrea
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Jun 19, 2021·Journal of Burn Care & Research : Official Publication of the American Burn Association·Eva FloresAbelardo Garcia de Lorenzo

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