Evaluation of low-level laser therapy, platelet-rich plasma, and their combination on the healing of Achilles tendon in rabbits

Lasers in Medical Science
Amin AllahverdiShahab Sarrout Dorbeh

Abstract

Tendon repair is still one of the challenges for rehabilitation. Various treatments for tendon injuries have been used in recent decade. This study was established to investigate the effects of low-level laser therapy (LLLT), platelet-rich plasma (PRP) treatment alone, and using combined method on the healing of Achilles tendon in rabbits. Seventy-two healthy mature male white New Zealand rabbits were divided randomly into four groups of 18 animals each: control: partial tenotomy with no treatment, only 1 mL normal saline was injected on days 1, 8, and 15 at the site of splitting; PRP: partial tenotomy with PRP treatment on days 1, 8, and 15 at the site of splitting; LLLT: partial tenotomy with LLLT (K30 hand-held probe, AZOR, Technica, Russia, 650 nm, 30 mW, surface area = 1 cm(2), 60 S/cm(2), energy density = 1.8 J/cm(2)) for 15 consecutive days; LLLT + PRP: partial tenotomy with LLLT + PRP. At the end of trial, the rabbits were euthanatized and tendon specimens were harvested and were submitted for histopathological evaluation, hydroxyproline levels, and biomechanical measurement. The Tukey post hoc test was performed. The results for these parameters showed that PRP or LLLT alone has significant advantages over untreated an...Continue Reading

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Citations

Oct 24, 2017·Frontiers of Medicine·Isabel Andia, Michele Abate
Feb 3, 2018·Veterinary Surgery : VS·Eric M ZellnerKarl H Kraus
Oct 26, 2018·Current Reviews in Musculoskeletal Medicine·Adrian D K LeJason L Dragoo
Nov 11, 2017·Journal of Lasers in Medical Sciences·Rafael BarbosaRinaldo Guirro
Jan 30, 2020·Animals : an Open Access Journal From MDPI·Laura CorteseAlessandra Pelagalli
Sep 22, 2016·Lasers in Medical Science·Guilherme Akio Tamura OzakiJosé Carlos Silva Camargo Filho
Oct 15, 2018·Lasers in Medical Science·Jihad A M AlzyoudAbd Al-Rahman S Al-Shudiefat
Nov 15, 2017·Future Science OA·Seyed Ahmad RaeissadatHossein Fouladi Vanda

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