Evaluation of malignant and benign renal lesions using diffusion-weighted MRI with multiple b values

Acta Radiologica
Gurcan ErbayNebil Bal

Abstract

Limited data are available regarding the use of diffusion-weighted (DW) magnetic resonance imaging (MRI) with multiple b values for characterization of renal lesions. To demonstrate and compare the diagnostic performance of DW-MRI with multiple b values for renal lesion characterization. Sixty-three lesions (36 malignant, 27 benign) in 60 consecutive patients (48 men, 12 women; age 60 ± 12.5 years) with solid/cystic renal lesion diagnosed after MRI were included prospectively. Single-shot echo-planar DW abdominal MRI (1.5T) was obtained using seven b values with eight apparent diffusion coefficient (ADC) maps. Contrast-to-noise ratios (CNRs), signal intensities, lesion ADCs, and lesion/normal parenchyma ADC ratios were analyzed. Receiver-operating characteristic analysis was performed. The mean signal intensities of malignant lesions (at b0, 50, and 200s/mm(2)) were significantly lower than those of benign lesions (P < 0.05). The mean ADC values at all b value combinations of malignant lesions were significantly lower than those of benign lesions (P < 0.000), excluding the ADC value at b50 s/mm(2). ADC with all b values could better distinguish between benign and malignant lesions. A 1.35 × 10(-3) mm(2)/s threshold ADC value pe...Continue Reading

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Citations

Dec 25, 2015·AJR. American Journal of Roentgenology·Andreas M HötkerOguz Akin
Oct 12, 2013·Journal of Magnetic Resonance Imaging : JMRI·Zafer Koc, Gurcan Erbay
Jul 24, 2015·AJR. American Journal of Roentgenology·Stella K KangBenjamin Littenberg
Jun 4, 2014·Radiologic Clinics of North America·Kumar Sandrasegaran

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