PMID: 2504229May 1, 1989Paper

Evaluation of needle exchange in central London: behaviour change and anti-HIV status over one year

AIDS
G J HartJ Parry

Abstract

From November 1987 to October 1988, numbers of clients, visits made and syringes dispensed and returned were monitored at the needle exchange of the Middlesex Hospital, London, UK. A sample of clients were interviewed 1 month after entry to the scheme and again 3 months later to evaluate changes in injecting and sexual risk behaviours for HIV infection. Clients were asked to donate saliva for anti-HIV immunoglobulin G (IgG) antibody capture radioimmunoassay (GACRIA). The rate of lending and borrowing used injecting equipment fell, both compared with rates prior to entry to the scheme and during the period of study. Frequency of injecting did not increase and there was reduced incidence of abscesses. There was a highly significant correlation between multiple sexual partners and condom use and a reduction in the proportion of clients with multiple partners. On entry to the study, seven out of 121 (6%) clients were anti-HIV positive; after 3 months, a further two clients tested were found to be anti-HIV positive. Anti-HIV positivity prevalence for the year of study was nine out of 121 (7%). The scheme attracts clients, reduces injecting-related risk for HIV infection and has high equipment return rates. Saliva testing is acceptab...Continue Reading

Citations

Jul 1, 1991·Behavioral Sciences & the Law·L Gostin
Jul 1, 1991·European Journal of Epidemiology·M GuiguetA J Valleron
Jan 1, 1994·Sozial- Und Präventivmedizin·K StarkR Müller
Nov 4, 2005·The New England Journal of Medicine·Rachel J Gordon, Franklin D Lowy
Feb 12, 1998·Medical Anthropology·J B Page
Oct 6, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·E A WalterL L Jagodzinski
Dec 23, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Walter T HughesUNKNOWN Pediatric AIDS Clinical Trials Group 254 Team
Sep 16, 1998·AIDS Research and Human Retroviruses·S J PopperP J Kanki
Jun 7, 2003·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Judith SneadBrian R Edlin
Jun 1, 1997·Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association·J A HahnA R Moss
Mar 1, 1994·The British Journal of Dermatology·V ZemelmanR C Staughton
Aug 1, 1996·Photochemistry and Photobiology·M Henry, E Tschachler
Nov 25, 1989·BMJ : British Medical Journal·O N GillN E Day
Jul 24, 1998·BMJ : British Medical Journal·J NellesT Harding
Feb 1, 1994·Journal of Epidemiology and Community Health·N P DicksonD C Skegg
Feb 1, 1991·Genitourinary Medicine·M W RossM E Miller
Jun 1, 2004·Harm Reduction Journal·Kate Ksobiech
Jul 18, 2003·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·Kate Ksobiech
Jan 8, 2000·Medical Anthropology Quarterly·J B Page, J Salazar Fraile
Oct 1, 1991·American Journal of Public Health·D D CelentanoK E Nelson
Jul 11, 1998·Substance Use & Misuse
Jan 1, 1995·The International Journal of the Addictions·D PaoneS R Friedman
Feb 22, 2012·Journal of Substance Abuse Treatment·Kristina T PhillipsKaren F Corsi
Nov 5, 1997·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·O P de AlmeidaS Porter
Jan 1, 1993·The Journal of Infection·R CovellN McKeganey
Sep 1, 1992·The Journal of Infection·R P Brettle
Aug 27, 2013·The International Journal on Drug Policy·Georgina J MacArthurSharon J Hutchinson

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