Evaluation of Nurses' and Patients' Overall Satisfaction with New and Previous Formulations of Octreotide Long-acting Release (Sandostatin LAR®): A French Observational Study.

Advances in Therapy
Brigitte DelemerGuillaume Cadiot

Abstract

The first long-acting release (LAR) formulation of octreotide was marketed in France in the late 1990s. An injectable formulation of Sandostatin LAR® (Novartis SAS) with a new diluent has been developed to facilitate its preparation and administration and to improve its use in practice. We conducted an observational, cross-sectional and multicenter study in France whose main outcome was to compare nurses' satisfaction with the preparation and administration of both previous and new formulations of octreotide LAR. Secondary outcomes included assessment of patient satisfaction (quality of life and pain felt during the injection) and product tolerance. Data were collected at two time points (one for the first formulation group and one for the second formulation group) through paper questionnaires administered to physicians, patients and nurses including a visual analog scale (VAS) from 0 (unsatisfied) to 10 (very satisfied). Results showed that overall nurse satisfaction improved from 5.3 (95% CI 4.9-5.8) with the previous formulation to 7.5 (95% CI 7-7.9) with the new formulation (p < 0.0001). Regarding secondary outcomes, the simplicity of the injection increased (84% for the previous formulation and 94% for the new formulation)...Continue Reading

References

Apr 1, 2005·Treatments in Endocrinology·John J Gilroy, R Andrew James
Feb 9, 2006·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·W R LenderkingC L Pashos
Oct 22, 2009·Current Medical Research and Opinion·Lowell Anthony, Pamela U Freda
Dec 1, 2009·Best Practice & Research. Clinical Endocrinology & Metabolism·Philippe ChansonJacques Young
Dec 19, 2015·International Journal of Nursing Practice·Julia CarlsonMathew Ku
Jan 9, 2016·European Journal of Endocrinology·Christian J StrasburgerN R Biermasz
Oct 13, 2016·Pituitary·Iris CrespoSusan M Webb
Sep 26, 2017·Therapeutic Delivery·Sarinj Fattah, David J Brayden
Jul 28, 2018·Nature Reviews. Endocrinology·Shlomo MelmedAndrea Giustina
Aug 21, 2018·Patient Preference and Adherence·Bernd Tischer, Andrea Mehl
Apr 3, 2020·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Louis de MestierUNKNOWN Thésaurus National de Cancérologie Digestive (TNCD)
Jan 1, 2017·Journal of the ASEAN Federation of Endocrine Societies·Shalini Sree Dharan, Nor Azmi Kamaruddin

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