Evaluation of optical rhinometry for nasal provocation testing in allergic and nonallergic subjects

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
Amber LuongPete S Batra

Abstract

Optical rhinometry is a new method that quantifies light extinction in optical density to assess nasal blood volume as a measure of nasal patency. The purpose of this study is to evaluate optical rhinometry as an objective evaluation of nasal patency using nasal provocation testing with histamine and oxymetazoline. Prospective pilot. Academic tertiary rhinologic practice. Convenience sample of five adult subjects with allergic rhinitis and five adult normal subjects who underwent challenge with histamine and oxymetazoline. Patients underwent challenge with increasing concentrations of histamine to determine the amount of histamine needed to cause a positive optical rhinometry reading. The same subjects then underwent histamine challenge with this amount followed by oxymetazoline. Nasal patency was assessed subjectively after each challenge with the visual analog scale. The median histamine amount needed to cause a positive response was statistically lower in allergic rhinitis as compared with nonallergic subjects at 150 microg and 300 microg, respectively (P = 0.04). When comparing the optical rhinometry with subjective nasal congestion after histamine and oxymetazoline challenges, there was a statistically significant correlat...Continue Reading

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Citations

Jul 22, 2010·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Esther J CheungAmber Luong
Jun 5, 2013·International Forum of Allergy & Rhinology·Elton M LambertAmber Luong
Jan 18, 2013·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Garima AgarwalAmber Luong
Oct 13, 2020·International Forum of Allergy & Rhinology·Denna ZebdaAmber U Luong
Oct 11, 2017·Otolaryngologic Clinics of North America·Michael J Marino, Amber U Luong

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