Evaluation of Outcomes Following Pulmonary Artery Stenting in Fibrosing Mediastinitis.

Cardiovascular and Interventional Radiology
John P WelbyErica M Knavel-Koepsel

Abstract

Fibrosing mediastinitis is a rare disease characterized by fibrosis of mediastinal structures with subsequent constriction of the bronchi and pulmonary vessels leading to potential respiratory compromise and death. Presently, there is no effective curative treatment with available treatments focused on reducing symptomology, including placement of pulmonary artery stents. Limited studies examine the use of stents in fibrosing mediastinitis. Given this knowledge gap, we assessed stent patency, hemodynamics, complications, and secondary outcomes of clinical improvement of pulmonary artery stenting for fibrosing mediastinitis. Nine patients with fibrosing mediastinitis and pulmonary artery stents were retrospectively identified for inclusion (six females, three males; mean age 44.17 years, range 13-68; total 13 primary stents) from 2005 to 2018. Eight patients had history of PH. All patients had dyspnea on presentation. Seven patients had ventilation/perfusion studies demonstrating impairment. Results from computed tomography and echocardiography studies were collected to assess patency and physiologic response. All patients received initial angioplasty and stenting of the right pulmonary artery (10 stents). Two patients underwent...Continue Reading

References

Dec 1, 1992·The Annals of Thoracic Surgery·D J Mathisen, H C Grillo
Sep 1, 1988·Medicine·J E LoydR M Des Prez
Feb 1, 1986·Chest·D F BerryK M Moser
Aug 1, 1994·Chest·A D SherrickJ L Myers
Mar 4, 2000·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·D E KandzariJ K Harrison
May 16, 2001·Radiographics : a Review Publication of the Radiological Society of North America, Inc·S E RossiJ R Galvin
Aug 25, 2001·American Journal of Respiratory and Critical Care Medicine·T P DoyleI M Robbins
Aug 25, 2001·Seminars in Respiratory Infections·A M DavisJ E Loyd
Sep 6, 2001·Journal of Vascular and Interventional Radiology : JVIR·A B FontaineC So
Jan 16, 2007·Clinical Microbiology Reviews·Carol A Kauffman
Apr 3, 2007·International Journal of Cardiology·Ruby SatpathyIjaz A Khan
Feb 23, 2008·Canadian Respiratory Journal : Journal of the Canadian Thoracic Society·Rennae ThiessenP Macleod
Apr 2, 2008·Heart, Lung & Circulation·C R Hamilton-CraigD L Walters
Jun 30, 2009·The Annals of Thoracic Surgery·Morgan L BrownHartzell V Schaff
Apr 24, 2010·Congenital Heart Disease·Matthew E FergusonDonald J Hagler
Mar 19, 2011·Journal of Interventional Cardiology·Damien KennyZiyad M Hijazi
Jul 25, 2012·AJR. American Journal of Roentgenology·Michael F McNeeleyJ David Godwin
Jan 18, 2014·The American Journal of Cardiology·Anna HallbergsonAudrey C Marshall
Nov 2, 2014·American Journal of Respiratory and Critical Care Medicine·Blair D WesterlyTobias Peikert
Nov 12, 2015·Medicine·Andrei SeferianDavid Montani
Mar 19, 2016·Journal of the American College of Cardiology·Matthew J LewisMarlon S Rosenbaum
Aug 2, 2017·Journal of Vascular and Interventional Radiology : JVIR·Omid KhalilzadehBoris Nikolic
Feb 23, 2019·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Erin A FenderDavid R Holmes

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