Evaluation of patients diagnosed with essential arterial hypertension through network analysis

Irish Journal of Medical Science
L SuciuM C Tomescu

Abstract

Essential hypertension is a chronic pathology that causes long-term complications due to late diagnosis of patients, the inability to control the disease through medication, or due to the complexity of associated risk factors. Our study sets out to identify specific patterns of response to arterial hypertension treatment, by taking into consideration the multiple connections between risk factors in a relevant population of hypertensive patients. Network science is an emerging paradigm, branching over multiple aspects of physical, biological and social phenomena. One such branch, which has brought significant contributions to medical science, is the field of network medicine. To apply this methodology, we create a complex network of hypertensive patients based on their common medical conditions. Consequently, we obtain a community-based representation which pinpoints specific-and previously uncharted-patterns of hypertension development. This approach creates incentives for evaluating patient's treatment efficacy, by considering its network topological position. Distinct clusters of patients with common properties have emerged for each study group (group A-treated with nebivolol, group B-treated with perindopril and group C-trea...Continue Reading

References

Mar 5, 2004·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·M E J Newman, M Girvan
Jul 27, 2007·The New England Journal of Medicine·Albert-László Barabási
Apr 28, 2009·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Andreas Noack
Jan 29, 2010·Diabetes Care·UNKNOWN American Diabetes Association
Dec 18, 2010·Nature Reviews. Genetics·Albert-László BarabásiJoseph Loscalzo
Sep 20, 2011·Wiley Interdisciplinary Reviews. Systems Biology and Medicine·Joseph Loscalzo, Albert-Laszlo Barabasi
Oct 16, 2012·Briefings in Functional Genomics·Kwang-Il Goh, In-Geol Choi
Jan 10, 2013·PLoS Computational Biology·Dong-Yeon ChoTeresa M Przytycka
Feb 20, 2013·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Albert-László Barabási
Jul 3, 2013·Journal of Hypertension·Nuno Cortez-DiasUNKNOWN VALSIM Study investigators
Mar 5, 2014·The Journal of Clinical Hypertension·Dina T ElperinRaoul J Burchette
Sep 3, 2014·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·David PapoEdward T Bullmore
Nov 11, 2014·The Journal of Clinical Hypertension·Teodoro MarottaAldo L Ferrara

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Related Feeds

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.