Evaluation of peri-infarcted hypoperfusion with T2*-weighted dynamic MRI

Journal of Magnetic Resonance Imaging : JMRI
C TsuchidaY Ishii

Abstract

The purpose of this study was to evaluate cerebral perfusion with T2*-weighted dynamic MRI in the area around the infarcted core. We examined seven patients with subacute cerebral infarction. After bolus injection a gadopentetate dimeglumine, a series of gradient-echo images were recorded in a selected slice. From these images, concentration-time curves were created on a region-of-interest (ROI) basis around infarction for calculating relative regional cerebral blood volume (rrCBV). Brain perfusion single photon emission computed tomography (SPECT) study also was performed with intravenous injection of 123I-labeled N-isopropyl-p-iodoamphetamine (123I-IMP). All patients showed prolonged signal decrease in the area around the infarcted core. ROI analysis showed significantly increased rrCBV compared to the normal side (P < .01, paired t test). The 123I-IMP SPECT study showed that these areas had decreased cerebral blood flow. Theses findings suggest compensatory vascular dilatation due to decreased perfusion pressure. T2*-weighted dynamic MRI is a useful method for detecting compensatory vasodilatation of ischemic insult in the peri-infarcted area.

References

Jun 1, 1991·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·B R RosenK K Kwong
Jun 1, 1991·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J KucharczykM Moseley
Oct 1, 1990·Stroke; a Journal of Cerebral Circulation·H YamauchiM Kameyama
Jun 1, 1990·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J W BelliveauT J Brady
Feb 1, 1988·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·A VillringerT J Brady
May 1, 1985·Stroke; a Journal of Cerebral Circulation·W J Powers, M E Raichle
May 1, 1973·Stroke; a Journal of Cerebral Circulation·R L GrubbM M Ter-Pogossian
Nov 1, 1984·Annals of Neurology·W J PowersM E Raichle
Nov 1, 1980·Stroke; a Journal of Cerebral Circulation·M TomitaK Tanaka
Feb 1, 1994·Current Opinion in Neurology·W D Heiss, R Graf
May 1, 1994·Journal of Computer Assisted Tomography·F GückelM Georgi
Jan 1, 1993·Topics in Magnetic Resonance Imaging : TMRI·P L Munk, A D Vellet

❮ Previous
Next ❯

Citations

Jul 6, 2000·AJR. American Journal of Roentgenology·J R Petrella, J M Provenzale
Jun 17, 1998·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·A E Baird, S Warach
Jul 21, 1999·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·F CalamanteR Turner
Jul 14, 2000·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Y LiuH J Aronen
Sep 20, 2000·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·W D Heiss
Nov 4, 2000·Stroke; a Journal of Cerebral Circulation·S L Keir, J M Wardlaw

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.