Evaluation of pharyngeal shape and size using anatomical optical coherence tomography in individuals with and without obstructive sleep apnoea

Journal of Sleep Research
J H WalshP R Eastwood

Abstract

This study compared shape, size and length of the pharyngeal airway in individuals with and without obstructive sleep apnoea (OSA) using a novel endoscopic imaging technique, anatomical optical coherence tomography (aOCT). The study population comprised a preliminary study group of 20 OSA patients and a subsequent controlled study group of 10 OSA patients and 10 body mass index (BMI)-, gender- and age-matched control subjects without OSA. All subjects were scanned using aOCT while awake, supine and breathing quietly. Measurements of airway cross-sectional area (CSA) and anteroposterior (A-P) and lateral diameters were obtained from the hypo-, oro- and velopharyngeal regions. A-P : lateral diameter ratios were calculated to provide an index of regional airway shape. In all subjects, pharyngeal CSA was lowest in the velopharynx. Patients with OSA had a smaller velopharyngeal CSA than controls (maximum CSA 91 +/- 40 versus 153 +/- 84 mm(2); P < 0.05) but comparable oro- (318 +/- 80 versus 279 +/- 129 mm(2); P = 0.48) and hypopharyngeal CSA (250 +/- 105 versus 303 +/- 112 mm(2); P = 0.36). In each pharyngeal region, the long axis of the airway was oriented in the lateral diameter. Airway shape was not different between the groups. ...Continue Reading

References

Sep 1, 1989·The American Review of Respiratory Disease·J L StaufferC W Zwillich
Oct 1, 1988·The American Review of Respiratory Disease·S T KunaC Ryckman
Nov 1, 1988·Journal of Applied Physiology·W B Van de Graaff
Apr 1, 1983·The American Review of Respiratory Disease·P M SurattS C Wilhoit
Jul 1, 1995·American Journal of Respiratory and Critical Care Medicine·D A PevernagieJ W Shepard
Mar 1, 1996·American Journal of Respiratory and Critical Care Medicine·J C Leiter
Sep 1, 1996·American Journal of Respiratory and Critical Care Medicine·C F Ryan, L L Love
Feb 1, 1996·Journal of Applied Physiology·S H LaunoisJ W Weiss
Feb 6, 1998·Journal of Applied Physiology·M J Morrell, M S Badr
Dec 16, 1998·American Journal of Respiratory and Critical Care Medicine·M J MorrellM S Badr
Aug 10, 2000·American Journal of Respiratory and Critical Care Medicine·J B SchellenbergR J Schwab
Apr 20, 2001·The European Respiratory Journal·M A CiscarJ Basterra
May 15, 2003·American Journal of Respiratory and Critical Care Medicine·Richard J SchwabAllan I Pack
Mar 8, 2005·American Journal of Respiratory and Critical Care Medicine·Raanan ArensAllan I Pack
Oct 22, 2005·American Journal of Respiratory and Critical Care Medicine·Julian J ArmstrongPeter R Eastwood

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Citations

Nov 4, 2010·Respirology : Official Journal of the Asian Pacific Society of Respirology·Harvey O CoxsonDon D Sin
Aug 19, 2011·Respirology : Official Journal of the Asian Pacific Society of Respirology·Simon A JoostenGarun Hamilton
Sep 21, 2010·American Journal of Respiratory and Critical Care Medicine·Jonathan P WilliamsonPeter R Eastwood
Apr 8, 2011·American Journal of Respiratory and Critical Care Medicine·Peter D Paré
Nov 30, 2014·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·Tomonori IwasakiYouichi Yamasaki
Oct 1, 2011·Expert Review of Respiratory Medicine·Randy HouMatt Brenner
Feb 20, 2009·Chest·Jonathan P WilliamsonPeter R Eastwood
Jun 4, 2013·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·Lígia Vieira ClaudinoEduardo Franzotti Sant' Anna
Feb 2, 2010·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Zachary R AbramsonLeonard Kaban
Apr 15, 2009·Optics Express·Robert A McLaughlinDavid D Sampson
Nov 28, 2009·Journal of Sleep Research·Mak Adam Daulatzai
Jun 17, 2010·IEEE Transactions on Bio-medical Engineering·A D LuceyD R Hillman
Oct 30, 2008·Optics Express·Robert A McLaughlinDavid D Sampson
Jun 2, 2015·American Journal of Respiratory and Critical Care Medicine·Clodagh M Ryan, Giora Pillar
Feb 24, 2015·Current Neurology and Neuroscience Reports·Julian P SaboiskySimon C Gandevia
Dec 10, 2009·Current Opinion in Allergy and Clinical Immunology·Wim G VosStijn L Verhulst
Mar 17, 2015·Sleep Medicine·Melinda JacksonMaree Barnes
Mar 21, 2017·Nature Reviews. Microbiology·Wing Ho ManDebby Bogaert
Jun 30, 2016·The Annals of Otology, Rhinology, and Laryngology·Giriraj K SharmaSunil Verma
Aug 6, 2015·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Hung-Chin ChenHsueh-Yu Li
Jan 24, 2019·Dysphagia·M StadingO Ekberg
Jan 23, 2010·European Journal of Applied Physiology·Arnoud BulckaertDaniel Berckmans
Apr 23, 2019·Cranio : the Journal of Craniomandibular Practice·Qiuyi Liang, Ronald Auvenshine
Mar 29, 2014·International Journal of Nursing Practice·Chun-Ja KimSe-Won Kang
Jan 31, 2015·Journal of Applied Physiology·Kristina KairaitisTerence C Amis
May 4, 2017·Journal of Texture Studies·Muhammad Qazi WaqasMats Stading
Jul 25, 2017·Biomedical Optics Express·Ruofei BuAmy L Oldenburg
Oct 12, 2019·The European Respiratory Journal·Peter R EastwoodSandrine H Launois
Jan 30, 2019·Annals of Biomedical Engineering·Ghazal AyoubEung Je Woo
Apr 11, 2020·Clinical Pharmacology : Advances and Applications·Rob TurnerTim Shea
Jun 19, 2018·Respiratory Physiology & Neurobiology·Melania MarquesAndrew Wellman
Jul 9, 2021·International Journal of Clinical Practice·Sanaz SadryHüseyin Kurtulmuş

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