Evaluation of postnatal weight growth in very low birth weight infants

Journal of Pediatric Gastroenterology and Nutrition
Enrico BertinoClaudio Fabris

Abstract

There is general agreement about the need for longitudinal studies of very low birth weight infants (VLBWI) to evaluate their postnatal growth and to generate distance and velocity charts that allow neonatologists and pediatricians to detect earlier whether a child is not growing adequately. There are no satisfactory growth charts for VLBWI. We analyzed the weight growth of 262 VLBWIs from birth to 2 years of corrected age. Individual growth profiles were fitted with a 7-constant exponential-logistic function suitable for modelling weight growth pattern. After a postnatal weight loss, all VLBWIs showed a late neonatal peak of velocity between the seventh and 21st weeks; the large majority of them also experienced an early neonatal peak between the second and the sixth weeks. Small-for-gestational-age VLBWIs with major morbidities grew less than reference appropriate-for-gestational-age VLBWIs without major morbidities: at 2 years, the difference in weight was about 860 g. The more severe growth impairment in VLBWIs with major morbidities was almost entirely due to the reduced height of the late neonatal peak of velocity. The mathematical function used in this study is expected to be a useful tool to trace model-based longitudin...Continue Reading

References

Aug 3, 1999·Pediatrics·R A EhrenkranzL A Papile
Apr 9, 2005·Pediatric Research·Patti Thureen, William C Heird
Sep 10, 2005·European Journal of Pediatrics·Mareike DiekmannMartina von Poblotzki
Apr 28, 2006·Archives of Disease in Childhood. Fetal and Neonatal Edition·E BertinoS Milani
Dec 23, 2006·Archives of Disease in Childhood. Fetal and Neonatal Edition·E BertinoM De Curtis

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Citations

Dec 12, 2007·Neonatal Network : NN·Margaret Shandor Miles

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