Evaluation of potential proton therapy utilization in a market-based environment

Journal of the American College of Radiology : JACR
Tomas Dvorak, David E Wazer

Abstract

Proton therapy is an increasingly prominent radiation treatment modality. Market-driven adoption of proton therapy into routine clinical practice may have a significant economic impact. The aim of this study was to estimate the proportion of patients who could potentially be treated with proton therapy by evaluating the utilization of existing highly conformal photon therapy as a proxy. All patients treated in 2007 with radiation therapy at the authors' institution were evaluated. Treatment technique was categorized using Current Procedural Terminology((R)) codes as conventional radiation therapy, intensity-modulated radiation therapy, Gamma Knife radiosurgery, stereotactic body radiation therapy, and brachytherapy. Medicare 2008 codes were used to estimate cost impact. One thousand forty-two patients were treated using 19,749 treatment fractions. As a potential proxy for proton therapy, highly conformal external-beam photon techniques were delivered in 31% of all fractions (intensity-modulated radiation therapy in 30%, stereotactic body radiation therapy in <1%, and Gamma Knife radiosurgery in 1%). Most were used for prostate cancer (37%), gliomas (17%), and head and neck cancers (16%). Pediatric patients were a small proporti...Continue Reading

References

Dec 1, 1982·Journal of Computer Assisted Tomography·S Komaki
Jun 23, 2005·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Ramona MayerThomas Auberger
Jun 25, 2005·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Marie Hélène BaronJoel Rochat
Aug 4, 2005·Cancer·Loren K MellArno J Mundt
Dec 8, 2005·Acta Oncologica·Bengt GlimeliusBjörn Zackrisson
Dec 8, 2005·Acta Oncologica·Jonas LundkvistBengt Glimelius
Mar 14, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Michael BradaDirk De Ruysscher
May 15, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Bengt Glimelius, Anders Montelius
May 15, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Dag Rune OlsenInger Natvig Norderhaug
May 16, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Mark LodgeTom Jefferson
May 22, 2007·International Journal of Radiation Oncology, Biology, Physics·Alexei TrofimovWilliam U Shipley
Aug 21, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Andre KonskiAlan Pollack
Jan 10, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Michael Goitein, James D Cox
Feb 2, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Herman SuitHarald Paganetti
Feb 12, 2008·International Journal of Radiation Oncology, Biology, Physics·Michael Goitein
Apr 15, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Dietmar GeorgRichard Pötter
Apr 30, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Joel E Tepper
Aug 19, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Madelon Pijls-JohannesmaYolande Lievens
Dec 30, 2008·Journal of the American College of Radiology : JACR·Edward C Halperin
Sep 17, 2009·Annals of Internal Medicine·Teruhiko TerasawaThomas A Trikalinos

❮ Previous
Next ❯

Citations

Dec 18, 2012·Journal of the National Cancer Institute·James B YuCary P Gross
Dec 18, 2012·Radiation Oncology·Maurizio AmichettiGiuseppe Minniti
Mar 12, 2013·Seminars in Radiation Oncology·Yolande Lievens, Madelon Pijls-Johannesma
Apr 2, 2014·International Journal of Radiation Oncology, Biology, Physics·John Kerstiens, Peter A S Johnstone
Mar 7, 2012·American Journal of Clinical Oncology·Tomas DvorakDavid E Wazer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
Evelyn Van de WerfYolande Lievens
Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
Mark LodgeTom Jefferson
Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
Herman SuitHarald Paganetti
© 2021 Meta ULC. All rights reserved