Evaluation of pre-hospital use of a valsalva assist device in the emergency treatment of supraventricular tachycardia [EVADE]: a randomised controlled feasibility trial

Pilot and Feasibility Studies
Andrew AppelboamEVADE study SWASFT collaborators

Abstract

The valsalva manoeuvre is an internationally recommended initial treatment for supraventricular tachycardia (SVT). The pre-hospital use of a valsalva assist device, to help deliver this manoeuvre, could improve cardioversion rates and reduce the need for patients to attend hospital. We conducted a randomised controlled feasibility trial comparing ambulance clinician use of a valsalva assist device versus standard care to treat adult patients presenting to an ambulance service in the south west of England. Eligible consenting participants were randomised 1:1 to device or standard care with trial procedures mirroring a proposed definitive trial.Feasibility was assessed upon ambulance clinician and participant recruitment rates and feedback, data completeness and potential future primary outcome rates. Over a 6 months period (1 July to 31 December 2018), 276 (23%) of 1183 eligible ambulance clinicians were trained and they recruited 34 participants; approximately 10% of patients presenting with suspected SVT during that time. Seventeen participants were randomised to each arm and all underwent their allocated valsalva strain method. All trial data and 63/68 (93%) of pre and post-valsalva ECGs were available. Seven (21%) participan...Continue Reading

Associated Clinical Trials

References

Jan 15, 1997·The American Journal of Cardiology·K A WoodM M Scheinman
Jan 13, 1998·Journal of the American College of Cardiology·L A OrejarenaJ J Hayes
Sep 2, 2004·Journal of the Royal Society of Medicine·Alec Buchanan
Dec 24, 2008·Emergency Medicine Journal : EMJ·G SmithM Boyle
Jan 1, 2008·Biomedical Imaging and Intervention Journal·A Vijayananthan, O Nawawi
Feb 11, 2015·BMJ : British Medical Journal·K HemmingR J Lilford
Jul 28, 2016·Emergency Medicine Journal : EMJ·Hilary Sarah ThorntonTimothy J Coats
Oct 1, 2016·Emergency Medicine Journal : EMJ·Leszek Pstras
Oct 26, 2016·BMJ : British Medical Journal·Sandra M EldridgeUNKNOWN PAFS consensus group
May 30, 2017·The American Journal of Emergency Medicine·Şeref Kerem ÇorbacıoğluHüseyin Uzunosmanoğlu
Sep 28, 2018·BMJ Open·Amanda Jane Blatch-JonesMartin Ashton-Key
Dec 7, 2018·Emergency Medicine Journal : EMJ·Isabel FitzGeraldAndy Appelboam

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Citations

Aug 19, 2021·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Eric Lodewyckx, Jochen Bergs

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Clinical Trials Mentioned

NCT03514628

Software Mentioned

ConSORT
SWASFT

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