Evaluation of preoperative risk factors and postoperative indicators for anastomotic leak of minimally invasive McKeown esophagectomy: a single-center retrospective analysis

Journal of Cardiothoracic Surgery
Chuan GaoDong Wang

Abstract

Minimally invasive McKeown esophagectomy is an important surgical approach for esophageal cancer. Anastomotic leak is one of its common and serious complications. We assumed that the preoperative risk factors and postoperative indicators would predict or detect anastomotic leak. Between December 2016 and July 2017, patients underwent minimally invasive McKeown esophagectomy were identified and their preoperative variables and postoperative test indicators were recorded. Fisher's exact test, 2-tailed unpaired t test, nonparametric test and logistic regression were used to compare these datum between patients with or without anastomotic leak (AL). Receiver Operator Characteristic (ROC) curve was used to identify the best cut-off value of drainage amylase concentration for distinguishing anastomotic leak. In all the 96 patients included, 12 patients were diagnosed as anastomotic leak by the esophagram. No differences in preoperative variables were observed between patients with and without AL. Patients in AL group appeared to have a lower prealbumin concentration in AL group on POD (postoperative day) 4(P = 0.05), POD 5(P = 0.04), POD 6 (P = 0.06). Prealbumin concentration cutoff value of 128 g/L on postoperative day 5 is 100.00% ...Continue Reading

References

Feb 5, 2005·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Richard D PageStephen H Pennefather
May 16, 2006·Thoracic Surgery Clinics·John D Mitchell
Aug 18, 2006·Cells, Tissues, Organs·Lucila BuschEnri Borda
Dec 14, 2006·Advances in Surgery·Linda W MartinJack A Roth
Jan 25, 2007·Annals of Surgery·Bernard M SmithersJanine M Thomas
Apr 3, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Randall P MortonNicholas P McIvor
Mar 28, 2008·ANZ Journal of Surgery·Justin KongJaswinder S Samra
Dec 11, 2008·Surgical Endoscopy·Darmarajah VeeramootooShahjehan A Wajed
May 30, 2009·Journal of the American College of Surgeons·James W MaherJohn M Kellum
Sep 29, 2011·The Annals of Thoracic Surgery·Robert E MerrittJoseph B Shrager
Apr 29, 2015·World Journal of Gastroenterology : WJG·Xu-Feng DengJi-Gang Dai
Aug 21, 2015·World Journal of Gastroenterology : WJG·Gijs H K BerkelmansMisha D P Luyer
Oct 16, 2015·Annals of Surgery·Sheraz MarkarUNKNOWN FREGAT (French Eso-Gastric Tumors) working group, FRENCH (Fédération de Recherche EN CHirurgie), and AFC (Association França
Sep 30, 2016·The Annals of Thoracic Surgery·Frans van WorkumCamiel Rosman

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Citations

Jul 12, 2019·Journal of Surgical Oncology·Bradley R HallBradley N Reames
Apr 10, 2020·The Journal of International Medical Research·Zhong-Wen SunHui-Ying Qin
Feb 11, 2021·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Antonio BarbaroJonathan Shenfine
Sep 30, 2021·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Alexander BullJames A Gossage

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