Evaluation of Quadrox-i and Capiox FX neonatal oxygenators with integrated arterial filters in eliminating gaseous microemboli and retaining hemodynamic properties during simulated cardiopulmonary bypass

Perfusion
J LinA Ündar

Abstract

Perfusion quality during cardiopulmonary bypass (CPB) procedures can contribute to postoperative neurological complications and influence patient recovery and outcome. Gaseous microemboli generated in the circuit and hemodynamic properties of blood reaching the patient can be monitored during CPB to optimize perfusion. Oxygenators that oxygenate the blood during CPB can significantly influence the quality of blood reaching the patient by their manufacturing designs. New hollow-fiber membrane oxygenators are developed with integrated arterial filters to reduce priming volume and eliminate a separate arterial filter in the circuit. To evaluate the performance of these new oxygenators, we used a simulated model to compare the Quadrox-i Neonatal and the Capiox Baby FX05 neonatal oxygenators and to provide a review of these oxygenators with their respective counterparts which have separate arterial filters. We found that microemboli counts for the new Quadrox-i and Capiox FX05 oxygenators are similar in the arterial line, but different across the oxygenator for all experimental conditions. The arterial purge line diverting blood from the patient reduces microemboli count for the Capiox FX05, but is inconsistent for the Quadrox-i Neo...Continue Reading

References

Jun 16, 2007·Ultrasound in Medicine & Biology·John E LynchJohn Sevick
Jul 23, 2008·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Shigang WangAkif Undar
Apr 28, 2010·Artificial Organs·Lee W Henderson
Apr 28, 2010·Artificial Organs·Xiaowei W Su, Akif Undar
Jan 1, 2011·World Journal for Pediatric & Congenital Heart Surgery·Joseph B ClarkAkif Undar

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Citations

Dec 11, 2019·Current Topics in Medicinal Chemistry·Anxin LiuShigang Wang

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