Evaluation of regional myocardial function by Doppler tissue imaging in univentricular heart after successful Fontan repair

Echocardiography
Pier P BassareoGiuseppe Mercuro

Abstract

The univentricular heart (UVH) corrected by Fontan repair is characterized by a single dilated pumping chamber, which is both hypertrophic and hypocontractile. The complex geometrical distortion and asynchronous contraction of this organ prevents assessment of systolic and diastolic function by traditional echocardiographic procedures. Sixteen children (10 males, 6 females) aged 12-31 years, who had undergone UVH Fontan repair were enrolled in the study. A transthoracic echocardiography was performed. Twelve different myocardial wall segments from single ventricles were studied by Doppler tissue imaging to measure peak systolic velocity (S), isovolumetric relaxation time (IRT), isovolumetric contraction time (ICT), and E'/A' ratio. S and E'/A' ratio were significantly lower in the UVH group than in controls (P < 0.01 and P < 0.05, respectively). IRT and ICT were significantly longer in UVH than in controls (P < 0.001 and P < 0.005, respectively). In the UVH, both systolic and diastolic deficits were generally registered in the apical segments and also randomly distributed between the basal and middle segments of the single ventricle. It is an acknowledged fact that compared to normal children ventricular function is impaired in...Continue Reading

References

May 1, 1971·Thorax·F Fontan, E Baudet
Oct 1, 1984·Journal of the American College of Cardiology·G BarberD J Driscoll
Dec 1, 1993·The Annals of Thoracic Surgery·A J ChinW I Norwood
Oct 1, 1993·Journal of the American College of Cardiology·T AkagiR M Freedom
Jan 29, 1999·Heart·D Sanchez-QuintanaR H Anderson
Mar 12, 2003·Journal of the American College of Cardiology·Mei WangJohn E Sanderson
May 17, 2005·Heart·Marc Gewillig
Jul 27, 2007·Echocardiography·Andrew T BurnsDavid L Prior
Feb 1, 2008·The International Journal of Cardiovascular Imaging·Leo H B Baur

❮ Previous
Next ❯

Citations

Mar 19, 2014·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Shu-Juan LiYiu-fai Cheung
Mar 7, 2020·Journal of Cardiovascular Medicine·Gaetano D GargiuloGiuseppe Calcaterra
Sep 29, 2020·Clinical Case Reports·Pier Paolo BassareoJohn Gerard Murray
May 11, 2021·Frontiers in Physiology·Sara MagnaniAntonio Crisafulli

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.