PMID: 11897975Mar 19, 2002Paper

Evaluation of REMEDi HS in the diagnosis of dimethoate poisoning

Therapeutic Drug Monitoring
Ralf RegenthalRainer Preiss

Abstract

The authors describe the evaluation of an automated rapid emergency drug profiling system (REMEDi HS), which is designed for clinical toxicology and therapeutic drug monitoring, in a severe case of dimethoate poisoning. Successful qualitative and quantitative determination of dimethoate in diluted serum samples was achieved. The authors found that dimethoate serum concentrations were properly measured with the REMEDi method and well correlated with gas chromatography-mass spectrometry. The results provide evidence that besides screening and rapid estimation of drug concentrations in human fluids, this system is a suitable tool in cases of symptomatic dimethoate poisoning.

References

Jan 1, 1988·Forensic Science International : Synergy·L Karalliedde, N Senanayake
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Oct 21, 1998·Therapeutic Drug Monitoring·I D Watson
Dec 29, 1998·Human & Experimental Toxicology·R RegenthalR Preiss

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Citations

Feb 16, 2006·Intensive Care Medicine·Ulrich Hoffmann, Thomas Papendorf
Jan 29, 2010·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Harald JohnHorst Thiermann

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