Evaluation of response to neoadjuvant chemotherapy for esophageal cancer: PET response criteria in solid tumors versus response evaluation criteria in solid tumors

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
Masahiro YanagawaJun Hatazawa

Abstract

Recently, PET response criteria in solid tumors (PERCIST) have been proposed as a new standardized method to assess chemotherapeutic response metabolically and quantitatively. The aim of this study was to evaluate therapeutic response to neoadjuvant chemotherapy for locally advanced esophageal cancer, comparing PERCIST with the currently widely used response evaluation criteria in solid tumors (RECIST). Fifty-one patients with locally advanced esophageal cancer who received neoadjuvant chemotherapy (5-fluorouracil, adriamycin, and cisplatin), followed by surgery were studied. Chemotherapeutic lesion responses were evaluated using (18)F-FDG PET and CT according to the RECIST and PERCIST methods. The PET/CT scans were obtained before chemotherapy and about 2 wk after completion of chemotherapy. Associations were statistically analyzed between survival (overall and disease-free survival) and clinicopathologic results (histology [well-, moderately, and poorly differentiated squamous cell carcinoma], lymphatic invasion, venous invasion, clinical stage, pathologic stage, resection level, reduction rate of tumor diameter, reduction rate of tumor uptake, chemotherapeutic responses in RECIST and PERCIST, and pathologic response). There ...Continue Reading

References

Jan 1, 1981·Cancer·A B MillerA Winkler
Apr 1, 1994·Clinical Pharmacokinetics·D J Morgan, K M Bray
Nov 15, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Gary L RosnerMark J Ratain
Nov 25, 2003·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Judith R KroepAdriaan A Lammertsma
Oct 16, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Mark J Ratain, S Gail Eckhardt
Apr 1, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Michael StahlHansjochen Wilke
Feb 3, 2006·The New England Journal of Medicine·Malik E Juweid, Bruce D Cheson
Apr 25, 2006·Nature Reviews. Cancer·Laura C Michaelis, Mark J Ratain
Sep 26, 2006·Best Practice & Research. Clinical Gastroenterology·Gerrit W Sloof
Apr 3, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Laurent BedenneChristine Binquet
May 2, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Robert S BenjaminChuslip Charnsangavej
Jun 17, 2008·The Oncologist·Annick D Van den Abbeele
May 13, 2008·Journal of the American College of Surgeons·James M McLoughlinRichard C Karl
Jul 25, 2008·The New England Journal of Medicine·Josep M LlovetUNKNOWN SHARP Investigators Study Group
Aug 15, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Johannes B RoedlMichael A Blake
Sep 5, 2008·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Johannes B RoedlMichael A Blake
Jun 24, 2009·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Richard L WahlMartin A Lodge
Jun 3, 2009·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Nabil P RizkValerie W Rusch
Oct 2, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Boris SepesiJeffrey H Peters

❮ Previous
Next ❯

Citations

Dec 7, 2013·Theranostics·Bing BaiPeter S Conti
Oct 10, 2013·Thyroid : Official Journal of the American Thyroid Association·Annibale VersariPaola Anna Erba
Aug 13, 2014·Nature Reviews. Clinical Oncology·Thomas E YankeelovC Chad Quarles
Nov 13, 2015·Expert Review of Gastroenterology & Hepatology·M A Blum MurphyJaffer A Ajani
Dec 29, 2012·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·D RousseauN Mesgouez-Nebout
Jun 20, 2015·Frontiers in Medicine·Thomas Carlier, Clément Bailly
May 26, 2009·Current Problems in Diagnostic Radiology·Xia Wang, Spencer Koch
Jan 21, 2016·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Troy Z HorvatPaul B Chapman
Oct 3, 2013·Asian Pacific Journal of Cancer Prevention : APJCP·Esengul Kocak UzelOmer Erol Uzel
Dec 11, 2013·Clinical Nuclear Medicine·Anna Margherita MaffioneDomenico Rubello
Jun 25, 2014·Oncology Letters·Ying LiuZhengqiu Zhu
Jun 1, 2017·Nuclear Medicine and Molecular Imaging·Ji-In BangKeon Wook Kang
Feb 3, 2018·Nuclear Medicine and Molecular Imaging·Joo Hyun O, Richard L Wahl
Apr 1, 2017·European Journal of Nuclear Medicine and Molecular Imaging·Katja PinkerWolfgang A Weber
Oct 23, 2015·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Emily C ZaborPaul B Chapman
Dec 18, 2020·Frontiers in Cell and Developmental Biology·Wenfang ChengJiancheng Li
Oct 19, 2013·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Secondo LastoriaFrancesco Perrone

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.