Evaluation of right ventricular systolic pressure during incremental exercise by Doppler echocardiography in adults with atrial septal defect

Chest
D A OelbergD Small

Abstract

Pulmonary hypertension is the most important complication in patients with atrial septal defect (ASD), but its role in limiting exercise has not been examined. This study sought to evaluate exercise performance in adults with ASD and determine the contribution of elevated pulmonary artery pressure in limiting exercise capacity. We used Doppler echocardiography during exercise in 10 adults (aged 34 to 70 years) with isolated ASD (New York Heart Association class I, II) and an equal number of matched control subjects. Incremental exercise was performed on an electrically braked upright cycle ergometer. Expired gases and VE were measured breath-by-breath. Two-dimensional and Doppler echocardiographic images were obtained at rest prior to exercise to determine ASD size, stroke volume (SV), shunt ratio (Qp:Qs), right ventricular outflow tract (RVOT) size, and right ventricular systolic pressure at rest (RVSPr). Doppler echocardiography was repeated at peak exercise to measure right ventricular systolic pressure during exercise (RVSPex). Resting echocardiography revealed that RVOT was larger (21+/-4 vs 35+/-8 mm, mean+/-SD; p=0.0009) and RVSPr tended to be higher (17+/-8 vs 31+/-8 mm Hg; p=0.08) in ASD; however, left ventricular SV w...Continue Reading

References

Oct 1, 1978·The American Journal of Cardiology·G R Cumming
Dec 13, 1990·The New England Journal of Medicine·J G MurphyG K Danielson
Mar 1, 1969·The American Journal of Cardiology·S J GoldbergR Hurwitz
Mar 1, 1970·The American Journal of Medicine·M D FlammE W Hancock
Nov 1, 1970·British Heart Journal·M Campbell
May 1, 1968·Circulation·R J Craig, A Selzer
Jan 1, 1966·The American Journal of Cardiology·M H FrickT Somer
Sep 1, 1966·British Heart Journal·H Davies, N Gazetopoulos
Feb 1, 1984·The American Review of Respiratory Disease·J E HansenK Wasserman
Jan 15, 1984·The American Journal of Cardiology·J K Perloff
Aug 24, 1995·The New England Journal of Medicine·S KonstantinidesW Kasper
Dec 15, 1993·The American Journal of Cardiology·F MeijboomE Bos
Feb 1, 1993·Circulation·J D RobertsW M Zapol

❮ Previous
Next ❯

Citations

Jun 23, 2001·Journal of the American College of Cardiology·G R VeldtmanP R McLaughlin
Jul 1, 2008·American Journal of Physiology. Heart and Circulatory Physiology·Takashi UrashimaDaniel Bernstein
Jun 28, 2011·Journal of Cardiopulmonary Rehabilitation and Prevention·Alexander Van De BruaeneWerner Budts
Jul 4, 2012·Heart Failure Clinics·Eduardo Bossone, Robert Naeije
May 13, 2005·Chest·Eduardo BossoneLuigi Allegra
May 22, 2009·Journal of Morphology·Devon E Quick, John A Ruben
Dec 19, 2007·Journal of Interventional Cardiology·Leonhard BruchFranz X Kleber
May 24, 2005·International Journal of Cardiology·Manfred WonischWerner W Klein
Feb 13, 2001·The American Journal of Cardiology·P M FredriksenG Webb
Sep 23, 2014·Echocardiography·Michele D'AltoRobert Naeije
Jul 9, 2009·Journal of the American College of Cardiology·David B BadeschAdam Torbicki
Dec 20, 2014·European Heart Journal Cardiovascular Imaging·Charlien GabrielsWerner Budts
Nov 13, 2012·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Eduardo BossoneRobert Naeije
Mar 2, 2011·Circulation. Cardiovascular Imaging·Alexander Van De BruaeneWerner Budts
Oct 26, 2018·European Journal of Preventive Cardiology·Francesca M RighiniPiergiuseppe Agostoni
Jun 28, 2016·Echo Research and Practice·Garvan C KaneRobert B McCully
Jun 17, 2019·The International Journal of Cardiovascular Imaging·Sigurdur S StephensenMarcus Carlsson

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autism

Autism spectrum disorder is associated with challenges with social skills, repetitive behaviors, and often accompanied by sensory sensitivities and medical issues. Here is the latest research on autism.