Evaluation of septal hypertrophy and systolic function in diseases that cause left ventricular hypertrophy: a 3-dimensional echocardiography study

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
J FrielingsdorfF A Flachskampf

Abstract

The goals of this study were to determine regional systolic function of the septum and to relate it to regional wall thickness and wall stress. Wall thickening, a parameter of systolic function, is determined by wall thickness and wall stress. In patients with hypertrophic obstructive cardiomyopathy (HOCM), hypertrophic nonobstructive cardiomyopathy (HNCM), and hypertensive heart disease (HHD), regional systolic function of normal and hypertrophic septal regions has been incompletely characterized by 2-dimensional echocardiography. Thus, multiplane transesophageal echocardiography with 3-dimensional reconstruction of the septum was used. In 49 patients (15 controls, 11 with HOCM, 8 with HNCM, and 15 with HHD) 4 parallel (2 basal and 2 apical) equidistant short-axis cross sections from base to apex were obtained from the reconstructed septum. In each short-axis cross section, 6 wall-thickness measurements were made in 15 degrees intervals at end diastole and end systole, for a total of 48 measurements in each patient. Fractional thickening was calculated as wall thickening divided by end-diastolic wall thickness. Wall thickness of the basal cross sections was significantly thicker (P < .001) in HOCM and HNCM than in HHD. However...Continue Reading

Citations

Oct 8, 2005·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Tsuyoshi MatsunakaJitsuo Higaki
Feb 26, 2009·Angiology·Dimitris P Papadopoulos, Vasilios Papademetriou
Dec 26, 2015·European Heart Journal Cardiovascular Imaging·Jonathan C L RodriguesNathan E Manghat
Jan 24, 2018·Journal of Applied Physiology·Fatih YalçinTheodore P Abraham

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