Evaluation of serum L-FABP levels in patients with acute pancreatitis

Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
Erdem KoçakGürhan Adam

Abstract

The aim of this study was to assess the serum L-FABP levels in patients with acute pancreatitis and compare with healthy subjects. Thirty patients with acute pancreatitis and thirty consecutive healthy age- and sex-matched control subjects were included into the study. The serum levels of L-FABP were measured upon admission and at the remission period. Upon admission, serum L-FABP concentration was significantly higher in patients with acute pancreatitis compared to control subjects (41009.41 ± 32401.31 pg/ml vs. 17057.00 ± 5015.74 pg/ml, p=0.008). Serum L-FABP levels decreased after the remission period; however, the differences were not statistically significant. In addition, serum L-FABP levels showed significant correlation with AST and LDH levels. Increased serum L-FABP levels may be related to the mechanism of pancreatic microcirculatory disturbance in patients with acute pancreatitis, suggesting that serum L-FABP could be used for a potential biomarker of acute pancreatitis.

Citations

Apr 18, 2016·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Zhaoyan QiuQingchuan Zhao
Feb 13, 2019·Dose-response : a Publication of International Hormesis Society·Huan YangJinFeng Yao

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