Evaluation of Serum Thiamine and Pyridoxine Levels in Patients Undergoing Liver Transplant: A Prospective Study.

Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation
Sami AkbulutSezai Yilmaz

Abstract

This prospective study aimed to compare changes in serum thiamine and pyridoxine levels of patients who underwent liver transplant or living donor hepatectomy. Between January 2013 and November 2013, 35 patients with chronic liver disease who underwent liver transplant (the recipient group) and 30 healthy individuals who underwent living donor hepatectomy (the control group) during the same period were prospectively compared in terms of both preoperative and postoperative serum thiamine and pyridoxine levels. The groups were also subjected to intragroup analysis of preoperative and postoperative changes in serum vitamin levels to determine how a major surgical procedure affected serum vitamin levels. Mann-Whitney U test and Wilcoxon signed-rank test were used for intergroup comparisons and intragroup repeated measurements, respectively. The intergroup comparisons revealed significant differences in favor of the control group with respect to preoperative thiamine (P < .026) and postoperative thiamine (P < .017) levels, whereas there were statistically significant differences in favor of the recipient group with respect to the preoperative pyridoxine (P < .006) and postoperative pyridoxine (P < .001) levels. The intragroup compar...Continue Reading

References

Mar 26, 2002·Digestive Diseases and Sciences·Stéphane LévySerge Erlinger
Dec 17, 2011·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Rakesh Kumar GuptaRam Kishore Singh Rathore
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Oct 26, 2012·Clinical Chemistry and Laboratory Medicine : CCLM·Charles H Halsted

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