Evaluation of simethicone for the treatment of postoperative abdominal discomfort in infants

Journal of Clinical Anesthesia
T D Voepel-LewisA R Tait

Abstract

To determine whether abdominal discomfort is a cause for distress symptoms in infants following administration of inhalational anesthesia, and to evaluate the effectiveness of simethicone in treating this discomfort. Randomized, double-blinded study. Large tertiary care, university-based medical center. 175 ASA physical status I and II infants under 28 months of age who underwent an inhalational anesthetic for a variety of procedures that were expected to cause relatively little pain. Children were assessed for the presence of postoperative abdominal discomfort, and, if evident, were randomly given either simethicone or placebo in a double-blinded fashion. Abdominal discomfort was measured using the Faces Legs Activity Cry and Consolability (FLACC) Behavioral Pain Scale. Scores were recorded pre-drug; at 10, 20, and 30 minutes following drug administration; and at discharge. If discomfort had not resolved within 15 minutes after the drug was given, routine analgesics or other medications were administered. Abdominal girth was measured preoperatively, on admission into the postanesthesia care unit (PACU), and at discharge. 21% of infants exhibited symptoms of abdominal discomfort postoperatively. Younger infants were at greater ...Continue Reading

References

Mar 1, 1975·Canadian Anaesthetists' Society Journal·G B Lewis
Apr 1, 1990·Acta Anaesthesiologica Scandinavica·J HovorkaO Erkola
May 1, 1985·Acta paediatrica Scandinavica·B Danielsson, C P Hwang
Dec 1, 1984·European Journal of Pediatrics·M R Ståhlberg

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Citations

Jul 26, 2008·Journal of Medical Case Reports·Ozlem GuneyselMurat Saritemur
Jan 8, 2015·Nurse Education in Practice·Linda M Veltri
Apr 12, 2007·Journal of Advanced Nursing·Jan ReedMargaret Cook
Jan 26, 2012·New Directions for Youth Development·Jane Elizabeth PizzolatoMary Allison Kanny
Jan 31, 2008·Journal of Speech, Language, and Hearing Research : JSLHR·Christopher DromeyRay M Merrill

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